“highly significant”

T-test comparison of SA versus UD means for discriminant function score, paired by clinician, replicated the overall results with a highly significant mean difference 1.77 points (p = 0.0003).

In particular, these data were highly significant in Codon 12 ( p = 0.0003).

In vascular surgery, the difference in the glitch rate between site E (mean of 6.3 glitches/hour) and site D (mean of 10.5 glitches/hour) was highly significant, p=0.0003.

Application of nicotinic PAM after xanomeline yielded a highly significant increase in peak amplitude (paired t -test, t 11 = 5.3, P = 0.0003; Fig. 5B ), charge transfer (paired t -test, t 11 = 4.7, P = 0.0007; Fig. 5C ) and rise speed (paired t -test, t 11 = 5.7, P = 0.0001; Fig. 5D ).

Genotype effects were also highly significant for SV2A in the hippocampus (F = 14.67, df = 1,56, P = .0003), amygdala (F = 14.48, df = 1,53, P = .0004), and striatum (F = 4.59, df = 1,53, P = .03).

Overall the tetanic stimulation resulted in a highly significant alteration in the EPSP-IPSP patterns (p=0.0003; Rank-Sum-Test).

Amygdala activation Investigation of amygdala activation revealed a highly significant pre–post intervention decrease in activation in a cluster in the right amygdala for the collapsed GAD sample in response to neutral facial expressions (p = 0.0003, size mm 3 :784, MNI coordinates x,y,z:30,− 5,− 19; Z = − 3.77).

However, pmax decreased across gestation in overweight/obese women, whereas it increased for normal weight women ( Figure 2a ); this difference in rate of change between groups was highly significant ( P =0.0003).

Among these, four genes showed high statistical significance ( G2E3, p = 0.0031, FC = 1.9; ZNF695 , p = 0.0096, FC = 2.0; CEP41 , p = 0.0023, FC = 2.2; RGPD1 , p = 0.0031, FC = 2.9), whereas the remaining six genes were highly significant ( NOL4, p = 0.0003, FC = 3.1; SOX6, p = 0.0003, FC = 3.2; GOLGA6C, p = 0.0002, FC = 5.9; PCDHA9, p = 0.0001, FC = 11; GOLGA6B , p = 0.0009, FC = 4.1; LMLN , p < 0.0001, FC = 3.4).

The cognitive performance, measured in the Y-maze task, revealed similar highly significant defects in GSK3α.KO and GSK3α.KOxTau.P301L mice in the number of entries and in alternations (p=0.0003 and p=0.0007 respectively; Table 2 ), although the index did not differ between either type of GSK3α-deficient mice and their respective controls.

Among all disease groups, a highly significant association ( p = 0.0003) of the rs1333049 variant was found with MetS/MetS-CHD − showing C allele carriers at a 4.04 times higher risk of MetS compared with non-carriers (OR = 4.04, 95% CI = 1.62–10.07).

Surgical resection was a highly significant factor reducing the risk of death by 74% ( P = 0.0003; hazard ratio 0.26, 95% C.I. 0.12 to 0.55).

That change is small when compared to the TfR-siFLUC negative control but highly significant ( p = 0.0003) when compared to the saline-treated group ( Figure 3(c) ).

The CD4+ T-cell count and sCD14 levels showed a highly significant negative correlation at BL (ρ = −0.42, p = 0.0003) ( Figure 4A ) and at w72 (ρ = −0.32, p = 0.007).

Using toluidine blue staining for dermal MC counts, a highly significant reduction was observed in the adelmidrol-treated side ( P = 0.0003) (Figure 3 ).

All immunized mice except a single animal from each vaccine treatment were protected and survived challenge (94% survival) which was highly significant in comparison to naїve mice (25% survival, p = 0.0003; Figure 2E ).

A regression for the likelihood of infection with genotype 2 or 3 at only low-elevation revealed a highly significant effect of log (Capture) ( p = 0.0003) (goodness of fit test, p = 0.97), with the probability of infection with these genotypes again decreasing as mosquito capture rate increased (Figure 2 B).

Further to this, the promoter SNPs had highly significant associations with pHULT ( p = 0.0003) in the Large White breed, an association which was not observed with I199V .

On day 7, there was a highly significant difference among instruments ( p = 0.0003), with the laser showing higher scores compared with the electrosurgical scalpel ( p = 0.0054).

A highly significant difference in the wild type mtDNA copy number per μm 3 between COX-intermediate reacting and COX-normal muscle fibres ( P < 0.0003) and between COX-intermediate reacting and COX-deficient muscle fibres ( P < 0.0004) was noted, providing further evidence that wild-type mtDNA copy number is the criti

The interaction between B-Current and C-pH (BC) was highly significant (F = 38.13, P = 0.0003), indicating that the effect of B-Current on COD removal efficiency is dependent on the C-pH level.

The comparison of the spectral counts in the inflammatory/immune category was highly significant ( Z = −3.16, P -value = 0.0003), while the comparison for all other proteins was not significant ( Z = 0.3602, P -value = 0.7206).

As would be predicted, a highly significant negative correlation was also observed between PARP activity and NAD + levels ( Fig. 6B , r = −0.638; p = 0.0003).

Consequently, the whole regression model was highly significant ( p = 0.0003) and had an explanation capability of 87.1% of the clinical outcomes.

The difference between the mean values of the two groups was highly significant ( P =0.0003).[ 36 ] Meanwhile, in the present study, the epidermis of HCV liver disease patients showed significantly lower thickness than the control group ( P =0.000) when measured by computer image analysis (histometry).