“highly significant”

These groups demonstrated highly significant improvements in OS (Bm2 hi /CCL3 lo HR = 0.14 (95%CI:0.04–0.49) p = 0.0004; Bm2 hi /CCL4 lo HR = 0.21 (95%CI:0.08–0.57), p = 0.001; and Bm2 hi /CXCL8 lo HR = 0.29 (95%CI:0.11–0.76), p = 0.007, Figure 5 ).

In the stunting model, Factor 2 showed a highly significant positive effect ( p = 0.0004; OR = 1.2368), implying that higher pre‐ and post‐monsoon temperatures are linked to higher odds of stunting.

Regression analysis using BMI as an ordered categorical variable revealed highly significant differences in the effect of PNPLA3 genotype on HTGC among the 4 BMI groups (t-test; P=0.0004).

The fat contents of the studied plant revealed a highly significant variation ( p = 0.0004).

Despite the small sample size included in the database for this tissue ( n = 72), also in this case, the analysis highlighted a highly significant association ( P = 4 × 10 –4 ) between rs7164338 and CIB2 expression levels.

The secondary comparison between PZ and TZ across all 36 patients was adequately powered (Cohen’s d = 1.34, retrospective power > 99%), consistent with the highly significant difference observed ( p = 0.0004).

Also of note, 20 significant correlations were detected between selected outcomes including a moderate and highly significant correlation ( R = 0.59, p < 0.0004) between axial hypersensitivity and disc nerve sprouting.

Intriguingly, however, we observed a modest, yet highly significant positive correlation between FBXW7 and MYC expression, exclusively in the Luminal A-subtype of breast cancers (rho=0.28, p=0.0004) (Figure 4A ).

At the aetiology level, it is worth noting that in the traumatic brain injury group, we found a highly significant link between number of hypo-CDP voxels (r s = − 0.80, p = 0.0004) and the CRS-R score ( Fig. 6 .A).

The levels of VLDLR-AS1 were lower in the rmTBI samples compared to the no lifetime TBI samples, and this difference was highly significant ( p = 0.0004), indicating that VLDLR-AS1 is a strong, viable indicator of rmTBI.

When both GNI and temperature were included in a multiple linear regression model the effect of temperature on % primary glomerulopathies remained highly significant (p = 0.0004) whereas GNI lost significance (p = 0.288).

2–6 d old (= pooled 2–3 d old and 4–6 d old nestlings) and 7–9 d old nestlings, still showed highly significant differences between these two groups of nestlings (MANOVA, in each case P ≤ 0.0004; for Age, df = 3 and 87.0; and for Brood identity(Age), df = 3 and 256.04).

In our comprehensive analyses of 1422 TCS with state-of-the-art audiologic testing, cisplatin showed a highly significant dose-response relationship with hearing loss (p = 0.0004).

This difference was highly significant ( P = 0.0004); the average distributions were 64% ±17 gametocytes in the BM and 8% ±9 gametocytes in the PB (Fig. 3b ).

The association was found to be statistically highly significant (p = 0.0004).

Bonferroni-corrected post hoc paired T -tests revealed a highly significant difference between fluent and nonfluent ABM sequences for body stimuli ( t (23) = 6.3, P < 0.0004), but the corresponding difference for nonbody stimuli just failed to achieve significance ( t (23) = 2.7, P = 0.052).

We found that our decoder predicted the correct CA3 input pattern 71.4% of the time, which was highly significant compared to a shuffle distribution where CA3 input labels were randomly assigned (Figure 6e ; p = 0.0004; bootstrap test).

Indeed, when the sub-Saharan populations are excluded, there is a highly significant correlation between latitude and deletion frequency (linear regression; R = 0.95, P = 0.0004).

This difference is highly significant (p<.0004, Fisher’s exact test, two-tailed); furthermore, the sole novel nonsynonymous variant detected in an African-American POAG case ( Table 3 ) was not predicted to be pathogenic.

Conversely, the use of CL4-PNPs as a delivery vehicle for Cis-Pt, resulted in a highly significant inhibitory performance on tumor growth compared to free Cis-Pt ( P = 0.0004) and Cis-Pt@PNPs-SCR (P = 0.0009) (Fig. 6 a).

Indeed, ABA3 expression kinetics obtained after infection by prtE and outC are not significantly or weakly significantly different from that obtained after buffer inoculation ( p -value = 0.0830 and 0.0411, respectively) in contrast to the highly significant differences between the WT strain ( p -value = 0.0004) or the hrcC mutant ( p -value = 0.0006) and the buffer ( Figure 3 and Supplementary Table S2 ).

9.3 days (COVID), showing a 71% decrease in overall hospital stay; this was statistically highly significant (p = 0.0004).

When analysed separately, there was a highly significant association between haemoglobin and serum ferritin in patients with ID ( r = 0.16, p = 0.0004), whereas in patients without ID, this association was only of borderline significance ( r = −0.09, p = 0.03).

Self-reported engagement in muscle-strengthening exercise showed a similar pattern, with highly significant differences at all three follow-up times (p=0·0004, p=0·0004, and p=0·0006).

There was no difference in the slopes ( P = 0.58), but the difference in elevation was highly significant ( P = 0.0004), indicating that WT and M/Mt-CK −/− hearts do not share the same relationship for d P /d t max versus heart rate, but instead run in parallel (i.e. for any given heart rate, d P /d t max is lower in M/Mt-CK −/− hearts).