“highly significant”

The relative increase at the intervention park play-scape compared with the control park playground were highly significant from both T1 to T2 (IRR = 14.45, 95% CI = 4.15–50.28, p < 0.0005) and T1 to T3 (IRR = 24.19, 95% CI = 6.79–86.19, p < 0.0005).

In this subgroup, the correlation between systolic blood pressure and urinary excretion of 8-epi-PGF 2α was highly significant (r = 0.50, p = 0.0005.

Irrespective of the adjustments performed, Table 2 demonstrates a highly significant heterogeneity of SMRs across regions in Italy and in Germany ( P < 0.0005).

The age adjustment was highly significant (p<0.0005), with an estimated mortality increase of 13.7% (95% CI 7.4% to 20.3%) for each 1% increase in %≥65.

In comparison, NP‐UAEC linear correlations between AUC and V m change were more highly significant ( P < 0.0005) and more predictive in showing greater hyperpolarization as AUC increased for both the initial peak and sustained [Ca2+]i phases.

Risk of LE rose across the cardiovascular disease risk scores in a highly significant trend ( p = 0.0005) (see Fig. 1 ).

Although the treatment effect was highly significant [F (1,33) = 14.75, p = 0.0005], no interaction nor genotype effects were found ([F (1,33) = 1.356, p = 0.2526; F (1,33) = 0.8743, p = 0.3566], respectively, Fig. 2B ).

In addition, the net reclassification improvement and integrated discrimination improvement were highly significant in all multimarker lipid panels alone and when added to the base model in the training set ( P ≤ 0.0005), an observation that was reproduced in the test set using the models that were developed in the training set.

Tetramers with RNAmotifs Fisher’s p-values ≤ 0.05 (or the 1 st percentile of the p-value distribution in case of highly significant results) and empirical p-values ≤ 0.0005 were considered as enriched and retained for further analysis ( Table S5 ).

After controlling for the effects of the pastrel gene by including it as a covariate in the analysis, we found another highly significant QTL on chromosome arm 2R with a LOD score of 29.0 (Fig. 2 B; genomewide significance: P < 0.0005).

Serotonin There was a highly significant ( F (1109) = 23.15, p < 0.0005) main effect of genotype on midbrain serotonin levels with wildtype controls averaging 408.3 ± 9.0 and the MTKO mice averaging 476.1 ± 10.0 (Fig. 6b ).

Similarly, in univariate analysis, resistin showed a highly significant correlation with Lequesne index (PCC 0.324, p = 0.0005) that was markedly reduced after adjustment by confounders.

Differences were highly significant ( P < 0.0005).

Overall, we found a highly significant negative relationship between competitive success and yield in monoculture (linear regression; F 1,18 =27.117, R 2 =0.601, P <0.0005; Fig. 4b ).

The mean digital value of the percentage of positivity of 5mC immunohistochemical expression (5mC%) was lower in colorectal carcinoma in comparison to colorectal adenomas and control group with mean differences of (−0.27567 ± 0.03) and (−0.32567 ± 0.03), respectively; and both differences are highly significant ( P < 0.0005), whereas 5mC% was nonsignificantly lower in colorectal adenomas in comparison to control group ( P = 0.099) with a mean difference of (−0.05 ± 0.03) as shown in Table 4 .

Top associated gene sets overlapped across module builds with highly significant p values (Fisher’s test) with the exception of vacuolation ( Figure 1 C, red solid line indicates p = 0.0005).

Differences in the LARS score among QoL categories were highly significant ( p < 0.0005) ( Figure 2 ).

Repeated measures analysis of variance with reading rate with and without overlays as factors revealed a highly significant effect of overlay F (1,93) = 30.9, p < 0.0005 and a highly significant interaction term F (1,93) = 8.57, p = 0.004, indicating that the effect of overlays was greater among participants who reported that the overlay made the text easier and more comfortable to read.

The cortex comprised of 19 brain areas all showed a decrease in brain volume that was highly significant ( p = 0.0005) with a mean difference of −3.195.

Statistical analysis confirmed that phopsho-p53(Ser15)-induction in FBXW 7-mutant tissues was highly significant ( p < 0.0005) (Figure 5B ).

The mean age among females was five years higher than that in males (59.9 versus 54.9 years), which is a highly significant observation (P < 0.0005).

The difference between the genotypes of schizophrenia cases and controls containing the C allele was highly significant ( χ 2 = 15.3; P = 0.0005). 3.3.

The ANOVA results for tensile strength indicate that the quadratic model is highly significant (Model F = 35.51, p = 0.0005).

In the 1–2 leaf developmental stage group there was an average 2.7 fold reduction in the AqPDS level (Figure 4 ), which was much more consistent and highly significant at p < 0.0005.

A consistent and highly significant difference was observed between Group 2 and Group 5 across all thresholds ( p = 0.0005).