Indeed, the relative similarity score was highly significant (score = 0.82, p = 0.0009), indicating direct TBX3 binding to the Lef1 promoter, most likely triggering its transcriptional repression (Fig. 5 l).
← all phrases
“highly significant”
Sighted at
p=0.09
In the literature
Altiarchaea genomes, a highly significant negative correlation ( Pearson , cor = −0.77, p = 9 × 10 −4 ) could be observed, indicating that a greater distance led to greater dissimilarity (Supplementary Fig. 7 ).
However, no pairs of loci were found to be highly significant after correction for multiple tests ( P = 0.0009).
The results showed that patient identity had no significant effect ( P = 0.336), while time had a highly significant effect ( P = 9.00e-4).
We also observed highly significant similarities between MZs when only presence and absence were taken into account by the Jaccard method (not considering the number of samples per set, p = 0.0009).
On the basis of the previously observed frequency (3/8) of 2D colorectal cancer cell lines demonstrating CIITA methylation, this result of zero of 15 organoids nonmethylated is highly significant (probability-based P = 0.0009; Fisher exact P = 0.032).
However, when only the α-PD-L1 and α-TIM-3 versus the α-PD-L1 and α-TIM-3 plus DT group were compared with a Student's t -test the reduction was highly significant (p = 0.0009) ( Fig. 3A ).
The full model was highly significant ( P value = 0.0009), and many individual parameter estimates were significant, notably in the M. galloprovincialis lineage ( table 3 ).
It was stopped before completion for ethical reasons because there was a strong and highly significant positive difference for rC1-INH versus placebo in median time to beginning of relief (62 versus 508 min, P = 0.0009) as well as time to minimal symptoms (480 versus 1480 min, P = 0.0038).
When this cohort was stratified based on low and high FABP12 expression levels, the association between BIRC5 and patient survival became insignificant in the subpopulation with low levels of FABP12 (HR = 2.22, p = 0.56; Figure 6 E), but remained highly significant in the subpopulation with high levels of FABP12 (HR = 4.28, p = 0.0009; Figure 6 F).
Nevertheless, there was highly significant (p = 0.0009) and moderate heterogeneity ( I 2 = 46%) among studies.
The phospholipid phosphoethanolamine demonstrated the most highly significant difference between slow growing and control longissimus ( P = 0.0009) as shown in Table 2 and Fig. 3 .
The association between RLS and cryptogenic events in patients older than 60 years found in the OXVASC study (based on 112 detected PFOs) was consistent with two previous smaller bubble-TCD studies of older age groups (based on 44 28 and 31 29 PFOs; figure 1 ), yielding a highly significant pooled estimate (OR 2·35, 95% CI 1·42–3·90; p=0·0009; p heterogeneity =0·15).
None of the recurrent smokers continued smoking during the study period and showed a highly significant difference ( p = 0.0009) when compared with the non-recurrent smokers.
This 62% reduction of 0.95 coughs·h −1 (95% CI 0.507–1.417) was highly significant (p=0.0009, figure 5b , table 1 ).
In contrast, the study results indicated highly significant correlations between SM and chronic disease (χ 2 = 10.846, p = .0009) as well as the absence of medical insurance (χ 2 = 84.175, p = .0001) ( Table 4 ).
When conducting a Pearson's correlation analysis, a strong positive and highly significant relationship between SV2A protein levels, as detected by ELISA, and mRNA levels in the cerebral cortex as conducted by RT‐qPCR ( r = 0.56, p = 0.0009, n = 32) and hippocampal ( r = 0.48, p = 0.004, n = 32) homogenates were observed (Figure 5A, B ). ′′The [3H]UCB‐J binding level showed a strong positive correlation with the SV2A protein level in the cerebral cortex ( r = 0.76; p < 0.0001, n = 20), but no significant correlation was found in the hippocampus ( r = 0.35, p = 0.13, n = 20) (Figure 5C, D ).
A one-way ANOVA of abnormal images above the summits of the DSPs indicated a highly significant difference (p = 0.0009) with Group 2 having significantly fewer abnormal images.
On control surfaces, a highly significant increase in plaque accumulation was observed from Day 1 to Day 2 ( p = 0.0009), then a constant increase occurred each day until Day 5.
Pairwise F ST comparisons of the Dokdo Island population with other local populations indicated highly significant differences after the Bonferroni correction was applied ( p < .0009), with a range of 0.0175 (Wangdolcho Reef) to 0.0639 (Chujado Island; Table 3 ).
3 ) but all these differences were nevertheless highly significant ( P < 0.0009 and Cohen’s d > 0.66 for all measures; detailed statistical results are reported in Supplementary Results).
In the 1‐back condition, accuracy scores were 9.6% lower in survivors (mean = 84.3, SD = 9.1) than controls (mean = 93.3, SD = 5.5), which was highly significant between groups ( t (41) = −3.6, p = .0009).
Statistical testing showed highly significant differences between all four profiles ( p < 0.0009), regardless of building period.
Nevertheless, there was highly significant (p=0.0009) and moderate heterogeneity ( I 2 =46%) among studies.
The odds ratio (OR) for developing symptomatic brain metastasis in the HER2-positive versus HER2-negative population was highly significant at 8.26 (95%CI 2.09–35.60; p = 0.0009).