Pairwise F ST comparisons of the Dokdo Island population with other local populations indicated highly significant differences after the Bonferroni correction was applied ( p < .0009), with a range of 0.0175 (Wangdolcho Reef) to 0.0639 (Chujado Island; Table 3 ).
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Estimated NK cytotoxicity was 15.5% among women living within 200 m of truck routes compared with 26.2% among women living at greater distances, and this difference was highly significant ( p = 0.0009; data not shown).
late was also highly significant ( P = 0.0009).
post-earthquake differences in species abundance were highly significant ( Supplementary Table 3 ; pairwise tests after significant one-way PERMANOVA: 1997 vs. 2012: P = 0.0009; 2005 vs. 2012: P = 0.0015), while differences between the two pre-seismic samplings remained non-significant (1997 vs. 2005: P = 0.5131).
Statistical analysis revealed a highly significant interaction between sex and treatment (sham, LPS, or LPS plus DCA) ( P = 0.0009), indicating that the treatment effect on cardiac performance is sex specific.
In addition, a Mann-Whitney U test, as modified by Gao and Allison [ 6 ], which was newly implemented in OASIS 2, showed that the difference in maximal lifespan was highly significant ( P = 9.0×10 −4 ; Figure 1D ).
The subsequent meta‐regression analysis revealed that the risk of bias was a highly significant moderator of the placebo effect ( p = 0.0009), explaining 100% of the between‐study heterogeneity ( I 2 residual = 0%).
On the basis of the previously observed frequency (3/8) of 2D colorectal cancer cell lines demonstrating CIITA methylation, this result of zero of 15 organoids nonmethylated is highly significant (probability-based P = 0.0009; Fisher exact P = 0.032).
While wildtype cultivars had an average grain width of 3.97mm, mutant at10 STOP cultivars had a narrower width of 3.92mm and this difference was very highly significant (p=0.0009) suggesting a potential role for arabinoxylan-esterified phenolic acids in determining grain shape.
When this cohort was stratified based on low and high FABP12 expression levels, the association between BIRC5 and patient survival became insignificant in the subpopulation with low levels of FABP12 (HR = 2.22, p = 0.56; Figure 6 E), but remained highly significant in the subpopulation with high levels of FABP12 (HR = 4.28, p = 0.0009; Figure 6 F).
In each case, we counted ∼400 stained SW620 cells expressing LacZ or hTRM9L and observed a highly significant difference ( p = 0.0009) in GLUT1 expression.
However, when comparing the numbers of marked cell achieved at days 6 or 50 between the two viruses the differences are highly significant ( P <0.0009) with higher frequency of marking achieved by the ICP0Cre recombinant at both acute and latent time points.
The pollen viability analysis showed that the pollen fertility of S 14 generation was significantly higher than that of S 4 generation, and had a statistically highly significant difference ( P = 0.0009).
The association between RLS and cryptogenic events in patients older than 60 years found in the OXVASC study (based on 112 detected PFOs) was consistent with two previous smaller bubble-TCD studies of older age groups (based on 44 28 and 31 29 PFOs; figure 1 ), yielding a highly significant pooled estimate (OR 2·35, 95% CI 1·42–3·90; p=0·0009; p heterogeneity =0·15).
The deletions of 10q11.22 (CNV_4) demonstrated a highly significant association with the risk of childhood obesity in our study ( p = 9.1 × 10 −4 ).
Notably, IL-13 exhibited a highly significant raw P -value ( P = 9.25 × 10−4), further supporting its potential causal role, yet no outliers were detected, reinforcing the validity of the IVW results.
Using the same statistics as in TADs ( Permutation Test ), the overlapping between LADs and isochores is highly significant (p = 0.00093).
final echo decorrelation ( r = 0.102 , RMS error 0.122, p = 0.520 ), but were highly significant for ablation rate vs. decorrelation ( r = 0.331 , RMS error 0.352 ml min −1 , p = 9.3 × 10 - 4 ).
Subsequent analysis by Linear Regression was highly significant with p = 9.40×10 −4 , and empirical p -value calculation by 10,000 permutations of 1.0×10 −3 .
There were two p -values (after adjustment) that were highly significant by the edge-count test: p =9.4×10 −4 for H 0 : F luminal A ∗ = F luminal B ∗ and p =1.1×10 −3 for H 0 : F basal − like ∗ = F luminal B ∗ .
The results show a highly significant value for the paired t -test of intervention Group B and control Group C of the cases ( P = 0.000957).
The two sample groups showed a highly significant difference regarding the intralesional abundance of T. pedis DNA (U = 146, p = 0.0009599).
For that 4-week period of spring 2020, the relative search volume for all 6 diseases was elevated above the pre-COVID baseline to a highly significant degree ( P <.00096 for all 24 values, corresponding to each of the 6 search terms through that 4-week period).
Statistically highly significant differences between conventional and organic farm isolates were detected for resistance to erythromycin (56/145 vs. 4/41; p = 0.000961) and clindamycin (81/145 vs. 6/41; p = 6.985 × 10 −6 ), as well as for tetracycline resistance in the alternative farm isolates ( p = 0.0001873) ( Figure 2 B and Table S3 ).
In addition, functional annotation of differentially expressed genes also showed a highly significant enrichment of genes involved in the development of the epidermis ( P = 9.63 × 10 -4 ), which also included downregulation of SPRR1A and B, KRT16 and KRT17 in old samples.