The correlation between measured and simulated FT4 values was highly significant (Spearman’s rho=0.882, p<0.001, see Figure 4 ). 3.3 Computer Aided Thyroid Treatment Framework The established mathematical model was implemented in software packages to perform numerical simulation studies.
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Model Validation and Extraction Efficiency The statistical robustness of the experimental design was validated via ANOVA, confirming that the second-order polynomial models for TPC, TFC, FRAP, and DPPH were highly significant ( p < 0.001) across all leaf morphologies and extraction techniques.
A pre-specified subset analysis by cytogenetic risk category did show a highly significant benefit of induction GO in patients with favorable risk cytogenetics (79% versus 51% overall survival, P = 0.001).
On intergroup comparison, it was found that there was a statistically significant difference in terms of marginal adaptation ( P = 0.024) and retention ( P = 0.023), while a highly significant difference was observed in terms of surface texture and anatomic form ( P < 0.001) at the end of 1 year [ Table 1 ].
The results obtained are considered highly significant for P <0.001, significant for P <0.01, and insignificant for P <0.05 or P >0.05.
In the BH, HUN, and SLO populations, one locus showed significant deviation ( p < 0.05), while in the CRO population, one locus showed highly significant deviation ( p < 0.001).
Incidence of Citrus Canker and Huanglongbing In regard to citrus canker incidence on harvested fruits, a highly significant ( p ≤ 0.001) interaction was observed between the 19 late-season sweet orange selections and the two assessed harvest seasons, 2020 and 2021 ( Table 8 ).
All the values were statistically highly significant ( P <0.001). 56.62% and 56.41% improvement was reported in sandhisphutana (crepitations) in left and right knee joint, respectively, in group A, while in group B, crepitation improved to the extent of 44.83% and 46.67% in the same joints.
4.83 [0.41]), and this difference remained highly significant ( p < 0.001), confirming clear exposure contrast between the study groups.
Physicochemical Parameters There was a highly significant overall variation on dissolved oxygen ( F (6,56) = 33.85; P < 0.001) but not in temperature ( F (6,56) = 2.15; P > 0.05), pH ( F (6, 56) = 0.83; P > 0.05), and vertical transparency ( F (6, 56) = 0.47; P > 0.05) among the sampling sites (Tables 2 and 3 ).
With all thirteen variables included in the analysis, Kendall’s W was .866 and highly significant ( X 2 = 93.57, df = 12, P < .001), meaning there was strong agreement overall in variable ranking across communities.
Vaccination with N or LT alone led to a further and highly significant increase in BAL lymphocytes (LT versus C+ p<0.001; N versus C+ p<0.01), neutrophils ( Fig. 2C : LT versus C+ p<0.01; N versus C+ p<0.001) and eosinophils ( Fig. 2D : LT versus C+ p<0.0001, N versus C+ p<0.001).
Cardiovascular comorbidities were also significantly more prevalent in the PD group (χ 2 = 4.71, p = 0.030), whereas neurovascular disease was identified exclusively in PD patients, showing a highly significant difference between groups (χ 2 = 15.50, p < 0.001).
Statistical analysis demonstrated that this difference was highly significant ( p < 0.001), indicating robust overexpression of TET1 in AML.
Overall significance of the treatment effect is also highly significant (p<0.001).
The effect of time period on the score was highly significant (p < 0.001) for all variables except for appearance of genitalia (p = 0.025).
Since both dish and container random effects were highly significant (P<0.001), we included them in subsequent models.
A coefficient of determination (R 2 ) close to 1 indicates an excellent linear fit of the experimental density–temperature data, and statistical analysis confirms that the slope is highly significant ( p < 0.001).
Factorial ANOVA revealed highly significant effects of all tested factors (variety, pathogen, surface disinfection, and treatment) and their interactions (all p < 0.001), indicating a strongly context-dependent response.
As presented in Table 2 , a statistically very highly significant difference ( p < 0.001) was found between the viscosities of the NE (F5), NEG (F5G), and CR-APMG.
In the normal-flow subgroup, between-arm differences were pronounced and highly significant across all three outcomes: VSC (Δ −20.2 ± 33.2 standard vs. −55.1 ± 42.7 probiotic vs. −85.7 ± 34.0 zinc; p < 0.001), organoleptic (Δ −0.2 ± 0.7 vs. −0.9 ± 0.8 vs. −1.3 ± 0.8; p < 0.001), and HALT (Δ −11.4 ± 7.0 vs. −17.5 ± 7.0 vs. −22.8 ± 7.0; p < 0.001).
A two-tailed Student’s t-test indicated that the difference in total CFU was highly significant ( P <0.001).
To avoid multiplicity, mainly highly significant ( P < 0.001) clinically relevant ( r > 0.30) correlations were considered of interest.
Values of “*” indicate p < 0.05 (significant), “**” indicate p < 0.01 (highly significant), and “***” indicate p < 0.001 (extremely significant). 3.
Analysis of variance (ANOVA) showed that the quadratic regression models for both systems were highly significant ( p < 0.001), while the lack-of-fit terms were not significant ( p > 0.05), indicating good model fit and accurate prediction of interactions among multiple components.