“highly significant”

GR demonstrated a highly significant association (p < 0.001) with the time-to-event outcome, suggesting that higher GR values are associated with a shorter time to response, with a hazard ratio of 0.575 (95% CI: 0.489 - 0.677), indicating a 42.5% reduction in the hazard rate per unit increase.

There was a highly significant arm by time interaction for mean pain diary scores ( p < 0.001) with lower scores in curcumin than in HPR PlusTM and placebo group in week 6.

Of note, when stratifying the whole cohort by the occurrence of sorafenib maintenance, the difference in OS between CR1 vs CR2/PIF/relapse patients becomes highly significant, p < 0.001.

The change of ACR category depending on the presence or absence of an LNG-IUD proved highly significant ( p < 0.001).

As for the direct effect of sex on decomposition use, it was highly significant before the mediator was entered in the model ( p < .001); once the mediator was added, the direct effect decreased but remained significant ( p = .02), indicating partial mediation (see Figure 1 A).

The multivariate logistic regression analysis showed that the cases screened within three days of febrile illness was a highly significant predictor of LDMI [(aOR = 5.17 (95% CI 3.47–7.70; p < 0.001)], with the controlled effect of all other independent factors such as endemicity, season, and age (Table 5 ).

Analysis of molecular variance revealed a low level of genetic differentiation but this was highly significant (p<0.001) among the cattle populations.

Joint variance analysis using mixed-model ANOVA revealed highly significant effects ( p < 0.001) for both genotype (F = 73) and ratoon year (F = 2) factors, accounting for 37.43% and 0.68% of total variance, respectively.

The statistical significance between samples was evaluated by performing Student’s t -test, with p -values less than 0.05 regarded as statistically significant, p < 0.01 indicated highly significant difference, p < 0.001 indicated extremely significant difference. 3.

Degrees of significance were assessed using different rating values: * p < 0.05 (significant), ** p < 0.01 (highly significant), *** p < 0.001 (extremely significant), **** p ≤ 0.0001 (extremely significant), and non-significant ( p > 0.05). 5.

There was a highly significant difference among the three genotypes in this parameter (Kruskal-Wallis test H 2,313 = 14.89, p<0.001).

All effects of birth year-month, sex, and sow parity on the ADGs (except for sex effects on DGBW, and sow parity effects on DGPT and BFAT) were highly significant (p<0.001).

When we assessed the relationship between menstruation before and after using isotretinoin, we found that 40 participants (10.4%) from those with known regular periods before isotretinoin treatment had reported irregular periods after using isotretinoin, which is statistically highly significant ( p < 0.001).

Regression analysis of absorbed or digestible CP on CP intake yielded a highly significant linear relationship (r 2 = 0.97, p<0.001).

This 1.6-fold increase in fatal outcome frequency in the elderly was highly significant ( p < 0.001) and corresponded to an excess risk of death attributable to irAEs in older patients.

Animal trials It was found that there were very highly significant (p<0.001) differences between diet treatments for all the measured parameters (total DMI, LWG and gain:feed, in vivo viscosity, ME:GE, AME content, ME:Gain, DM retention, ileal dry matter, starch and protein digestibility).

The TSK-11 has good test-retest reliability (ICC (95% CI) 0.81 (0.71 to 0.88)) and a highly significant correlation with change scores on the TSK (r = 0.93, P < .001) [ 18 , 19 ].

Data presented in Table 2 indicated that breed had a highly significant impact on lightness and MS (p<0.001) for which the F values were 11.42 and 8.44, respectively.

Contrary to expectations, two-way ANOVA analysis of the skeletal phenotype at 6, 12, and 18 wk of age ( Figure 1b , Table 1 , Figure 1—figure supplement 1c , Supplementary file 1 ), revealed highly significant ( P <0.001) anabolic effects of Rspo3 haplo-insufficiency on structural, cellular, and dynamic parameters in both female and male mice.

Differences were considered significant when p ≤ 0.05 (*) or highly significant when p ≤ 0.001 (**).

The time of onset of sensory block was 6.57±1.794 minutes in group IB, 2.30±1.343 minutes in group HB, and 4.57±1.960 minutes in group IL, and this variation was statistically highly significant (P<0.001).

This difference was statistically highly significant ( p < 0.001).

In contrast, nestling-stage DSR decreased to 0.98 ± 0.00087, a highly significant reduction (z = 8.5, p < 0.001), resulting in a cumulative survival probability of 56.2%.

This difference was statistically highly significant ( P < 0.001).

Correlation analysis of MMP-9/BDNF ratio with parameters of interest for the clinical assessment of the disease severity ( Table 4 ) revealed its negative correlation with IL-10/IL-17 ratio in moderately ill patients (p<0.05) and highly significant positive correlation with MMP-8 in mild (I), moderate (II) and IV (critical) groups (p<0.001).