Except for the decrease in the phosphorylation level of AKT (just over the limits of statistical significance, p = 0.055) and 4EBP1 at HU1, no significant changes in the phosphorylation levels of AKT, mTOR, and 4EBP1 were found during disuse.
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“just over the limits of statistical significance”
Sighted at
p=0.06
In the literature
The results for DIE+OMA were not significant for any of the SNPs tested, expect for rs4703907 that was just over the limits of statistical significance ( P = 0.09).
Determinants of SBI In adjusted analysis, SBI occurrence was associated with AIDS stage (HR = 1.69, 95% CI: [1.33–2.14]) as well as with CDC B stage (HR = 1.45 [1.18–1.79]), HCV coinfection (HR = 1.37 [1.15–1.63]), history of cancer (HR = 1.37 [1.01–1.86]); the association with diabetes was just over the limits of statistical significance (HR = 1.55 [0.94–2.56]) ( Table 2 ).
Ruminococcus did not show any significant positive correlation, although correlations for propionic acid (r = 0.462, p = 0.053) and butyric acid (r = 0.452, p = 0.059) were just over the limits of statistical significance.
In fact, in our study, patients who presented a higher zenith VL (≥ 200,000 copies/ml) had a lower cerebral vascular reactivity measured by BHI than those with zenith CV < 200,000 copies/ml, which was just over the limits of statistical significance.