“likely to be significant”

First, we recognise that other enzymes of the aspartyl, cysteine and serine proteinase families and their specific inhibitors are also likely to be significant participants in ECM remodelling during cancer progression.

Therefore the role of HSP72, 73 and 90 is likely to be significant in chondrosarcoma.

The latter constraint may be relatively unimportant for mosquitoes and other flying arthropods but is likely to be significant for less mobile taxa such as ticks.

Table 2 shows a list of disorders associated with primary or secondary myelofibrosis; Table 3 shows conditions where the fibrosis is likely to be significant and, in some cases, may be associated with deposition of collagen) [ 8 , 9 ].

Hence, we can improve the seed selectivity by favoring hits at initial positions of the read where matches are more likely to be significant.

Prevotellaceae have been shown to be part of the core microbiota of C57Bl/6 mice ( Gu et al., 2013 ), as such the consequences of reducing the prevalence of Prevotellaceae is likely to be significant.

The implications of this for equality, diversity, and inclusion are likely to be significant, as is discussed when looking at what universities might do to overcome the negative impacts of C19.

Formation of isoAsp at several sites is likely to be significant in terms of the conversion of MBP to a novel antigenic form that could potentially act to trigger an immune response.

This is because, at low feed temperatures, the concentration polarization phenomenon is less likely to be significant as compared to high feed temperatures.

Individual pairwise coherence above the 95% confidence interval (CI) is likely to be significant, revealing true shared drive between the two muscles.

This lack of representation of LMICs is not surprising, and there are likely to be significant gaps in reporting of perinatal outcomes during the pandemic in these regions due to reduction of institutional births and staff available for data collection [ 25 ].

Konisky [ 16 ] found that for Hispanic communities, firms are not only more likely to be significant violators of their Clean Air Act obligations, but they are less likely to be designated as violators by regulatory offices.

Interestingly, the erythrocyte PPP and glycolytic pathways are likely to be significant sources of ROS in the circulation.

Other emerging issues reported in the literature that are likely to be significant barriers for teams of allied health, though not evident in the results of this study, are managing the role of consumers in research and the challenges of mixed methods, multidisciplinary approaches, and multinational research studies. 3 , 41 The results of this study identify differences in the motivators, enablers, and barriers that operate for the individuals and teams within an organization.

Although the etiology and the mechanisms responsible for the regulation of its growth are currently unknown, exposure to sunlight and ultraviolet light, previous irradiation, infection with Merkel cell polyomavirus (MCV), and immunosuppression are likely to be significant risk factors [ 1 , 6 ].

1985 ), the frequency of agent-misidentification errors caused by heuristics is likely to be significant and have major societal implications—for example errors in distributions of social punishments or benefits as in the conviction of innocents in judicial trials (Lampinen et al. 2012 ).

As above, a reduction of ≥25% from baseline was considered likely to be significant.

Discussion The key issues in deciding whether to introduce a new screening programme include whether: (1) screening represents a cost-effective intervention (i.e., the health gains are likely to be significant compared with the costs involved); (2) uptake is likely to be sufficiently high for screening to be effective; and (3) implementation is feasible (i.e., sufficient health service resources are available to diagnose, treat and follow-up those found to have adenomas and cancer).

Within studies, there were also likely to be significant individual patient differences and there may be an assumption that the cancer is causing weight loss, reduced function and loss of lean mass when it is possible that it may be multifactorial.

Therefore, eosinophilia, along with low CD4, CD8 T cells, and activated inflammatory response, are likely to be significant prognostic factors for the disease severity.

Furthermore, the IPTW generates more pseudo-populations, making statistical tests more likely to be significant.

Both procedures reduce the dataset to a series of pertinent discussions likely to be significant for intragroup relations and group decision-making.

While there are many factors determining whether a gene is activated or deactivated, it seems likely to be significant if the probability of a transcription factor is high for a branch of the phylogenetic tree and lower for the remaining species, or vice versa.

And yet, the experimental evidence for horizontal sweeps comes from communities of phylogenetically related strains 9 , 11 , 12 , 13 , 25 where ecological competition is likely to be significant.

This again suggested that more frequent seizures and co-infection were likely to be significant characteristics of RSV infection in the post-COVID-19 era and played important roles in the progression of RSV infection, reflecting the potential impact of COVID-19 pandemic on RSV infection.