Evaluation of surrogate endpoints Prentice’s criterion one The 5-year OS rate was 72 % in the CCRT group and 84 % in the NACT+CCRT group, with a marginally significant difference ( P log-rank = 0.050; Fig. 1 ).
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We consider these associations all as marginally significant since none survived multiple testing correction for false discovery rate (Supplementary Table 1 ).
The general results did not change and the associations were still significant or marginally significant.
Overall, the magnitude of the FID difference (that is, the effect sizes) of populations under low versus high human disturbance was lower, albeit marginally significant, in contrasts made ‘within' a same habitat type (for example, low versus high human disturbance in islands) than in contrasts made ‘between' habitat types (for example, rural versus urban areas; Q b =3.70, df=1, P =0.054).
[15] Line 376 – Where did the variance of 0.15 come from? Does this agree with the experimental data? [16] Line 395 – What is meant by “pre-culture”? [17] Line 419 – What is meant by “standard”? [18] Line 482 – “marginally significant” – The phrasing of these results in the conclusion on line 499-500 seems more appropriate.
In contrast, among students with co-residing smokers, the associations between tobacco-related unpleasant experience and SHS at home were apparently weaker and either marginally significant or non-significant.
In MRR2-2, unmarked Wb+ males showed reduced dispersal compared with fluorescent Wb+ males, and this trend was also marginally significant in MRR2-1 ( Figure 3 ).
In the absence of SHS, well children had a marginally significant relationship between ambient fine particulate matter and log(LTE4), while there was no apparent relationship when children were sick (last row, Table 3 ).
There was one significant and one marginally significant correlation between potential-amplitude data and baseline pleasantness ratings (taken before and after the task) at 926 ms.
5d ; Supplementary Data S4 ), suggesting that these biomarkers may have limitations in detecting patients with severe methylation maintenance loss, such as ASCL2 in LIHC, UNXC in LUSC, and SEPT9 in READ (FDA approved, marginally significant) ( Fig. 5e ).
In mutually-adjusted analyses these effects were attenuated but marginally significant effects remained for gender, age and area of London. 3.3 Reporting of fatalities outside London In all three non-London cities, the level of coverage of both cyclist and motorcyclist fatalities was uniformly high across the whole of the study period, including 100% coverage of cyclist fatalities in Bristol and Cambridge (see Table 3 ).
Higher non-leisure-time PA levels tended to be associated with lower odds of sarcopenia in women (P for trend = 0.1110); odds of sarcopenia tended to be higher in men (P for trend = 0.0639, marginally significant).
In addition, there was a marginally significant penalty for indefinite subject correlates ( M = 147 ms, SE = 10) compared to indefinite object correlates ( M = 125, SE = 10) on the spill-over region in second pass re-reading times, t = 1.95.
Higher Education, included in the final model, also shows a positive association, though marginally significant.
The results from the fully adjusted mixed effect logistic regression model was marginally significant, likely due to the reduced sample size within this sub-stratum, but was consistent in terms of direction with the results of the recursive partitioning analysis: i.e., among non-African American/Black participants in this older age strata who reported having friends or acquaintances in the neighborhood who differed in demographic characteristics from themselves, the odds of being obese were 1.2 higher than for those not reporting this type of neighborhood situation (95 % CI: 1.0, 1.4; p = .095).
In addition, war captivity did make a marginally significant contribution to PTSD severity at T5.
Comparison of hyperuricemic patients who did not use ULT (HUA /No gout /No ULT), to the matched reference group (No HUA /No gout /No ULT) showed a marginally significant effect on all-cause mortality (adjusted HR 1.24; 95% confidence interval (CI) 0.97–1.59) due to attrition of case number after matching procedure, and a significant risk of hyperuricemia for CVD mortality (adjusted HR 2.13; 95% CI 1.34–3.39) ( Table 2 ).
Individual SNP associations to the diseases The results of the conventional GWAS analysis render no significant associations (after multiple testing adjustments) for jPTC and only 21 SNPs with marginally significant associations for MTC (see Additional file 1 : Table S4).
When limited to extracolonic sites, the risk of non‐CRC MPC was still elevated compared to the corresponding risk of cancer in the general population with a SIR of 1.11 (95% CI: 1.08, 1.15; AER = 18.8, 95% CI: 16.9, 20.9); however, this significant elevation in risk was primarily in males (SIR = 1.10, 95% CI: 1.06, 1.15; AER = 21.4, 95% CI: 18.5, 24.5), while it was marginally significant in females (SIR = 1.05, 95% CI: 1.00, 1.10).
The halo study lacks control recordings from TRN and relay neurons to show what this manipulation does to thalamic activity, and the data provided are very limited in scope (measures of cortical delta power only) and marginally significant ( Figure 4D , right) with small effects.
In a cohort of Canadian women (519 cases) [ 46 ], a marginally significant protective association between total vitamin A intake, preformed vitamin A and β-carotene, and breast cancer was seen.
[ 23 ] concluded that both psychological interventions and physical activity had a marginally significant impact on reducing fatigue in adults with RA.
Despite being marginally significant, this value is chosen as a reference [ 43 ].
For patients, there were marginally significant treatment effects following IET on psychological well-being on the Psychological Well-Being Scale of Mental Health Inventory ( 28 ), while no significant treatment differences for partners were observed.
As a conclusion, for locally advanced nasopharyngeal cancer, no significant differences in the treatment efficacies of CCRT, IC + CCRT, and CCRT + AC were found, with the exception of a marginally significant improvement in distant control observed following IC + CCRT compared with CCRT alone.