Barely Significant
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may be significant

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In the literature

Two previous studies have also suggested that pain-symptom descriptors may be significant predictors of NeP severity. 28 , 29 In those studies, the presence of a higher number of descriptors, as well as specific descriptor qualities, had greater predictive value for more severe pain. 28 , 29 The range of descriptors constituting painDETECT overlaps with those descriptors that have shown predictive ability for pain severity.
Measurement properties of painDETECT by average pain severity.
Clinicoecon Outcomes Res · 2014 · PMC4226388
The time-period over which the tissue freezes is an important consideration as damage due to ice-crystal formation may be significant, thus altering the level of cellular or sub-cellular detail that can be preserved in the sample.
The simple definition as a diameter may be sufficient for a low accuracy application, but in a high accuracy situation imperfections from a perfectly circular workpiece may be significant. 2 Due to manufacturing imperfections, the diameter of a workpiece is incompletely defined and this can lead to “methods divergence problems” where different measuring instruments yield significantly different results.
A Careful Consideration of the Calibration Concept.
J Res Natl Inst Stand Technol · 2001 · PMC4862813
The expected improvement in psoriasis associated with weight loss may be significant but not too clinically relevant: weight loss following lifestyle interventions (diet or physical activity) improves psoriasis compared with control [mean change in Psoriasis Area and Severity Index − 2.59, 95% confidence interval (CI) − 4.9 to − 1.09; P < 0.001] [ 23 ].
Management of Obesity in Psoriasis Consultations.
Dermatol Ther (Heidelb) · 2026 · PMC12936324
Distinct from the CA1 and CA3 regions, which are selectively injured in BCCAO and BCAS chronic models, the CA2 region of the hippocampus is involved in social recognition memory and may be significant in the context of BCCAGO model behavioral and cognitive changes ( Piskorowski and Chevaleyre, 2023 ; Bennett et al., 1998 ; Soria et al., 2013 ; Khan et al., 2015 ).