Barely Significant
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may be significant

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In the literature

Furthermore, the serum levels of OPG were significantly higher in IDD patients with TT, TC and CC genotypes at the OPG rs2073617 locus, as compared with the control group (P<0.05), which suggested that TT, TC and CC genotypes may be significant risk factors for IDD development and that upregulated serum levels of OPG are correlated with IDD risk.
Understudied but perhaps of particular importance in these potential transmission events are companion animals, and it is becoming increasingly clear that they may be significant reservoirs, especially when their human caregivers are immunocompromised or have had spells in hospital [ 62 ].
However, in cases where children present with persistent microscopic haematuria often accompanied by episodes of visible blood in the urine (gross hematuria), there may be significant anxiety for both patients and their families, leading to a strong desire for a definitive diagnosis [ 28 ].
Alport Syndrome: A Comprehensive Review.
Cureus · 2023 · PMC10649250
It is tempting to speculate whether failure of CX 3 CR1 deficient cells to tubulate, or initiate differentiation into mural smooth muscle-like cells or impairment of extracellular matrix production may be significant contributors to increased microvessel porosity to blood and solutes in vivo thus providing a mechanism underlying the leaky MV phenotype.
Similarly, patients with consistently resistant strains also had in- fections with a variety of serological types: 11 had type 19 infections, 2 type 30, and one each type 6, 18, or 38 infections. Although an insufficient number of strains of the various serological types were available to determine whether this variation has any relationship to the type or is characteristic of particular strains, some of the data may be significant in this respect.