Those patients with significant hemodynamic changes may present congestive heart failure or in the long-term may develop irreversible changes in pulmonary vascularity leading to pulmonary hypertension.[ 9 ] There may be significant co-morbidity including pulmonary edema and bleeding, bronchopulmonary dysplasia (BPD), intraventricular hemorrhage (IVH) bleeding, necrotizing enterocolitis (NEC), feeding intolerance and retinopathy of prematurity (ROP).[ 9 ] However, in recent articles the effect of ductus closure on mortality and
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In the literature
IDE activators with desirable pharmacokinetic properties may be significant for diabetes, as it is questionable to combat with diabetes or hyperinsulinemia through genetic mutations of IDE gene [28] .
This may result in a situation that the Pearson correlation coefficients may be significant, but not especially strong.
Cardiac TnT has a 32-amino acid N-terminal extension rich in negative charges and may be significant for the cardiac-specific role of TnT.
Third, it is obvious that the dose of the ingestion, duration between the ingestion and presentation to the ED, comorbidities, coingestions, medical history, severity of the disease process, quality of the treatment, level of the hospital, and expertise of the providers may be significant confounders, therefore, all conclusions should be corrected for those variables.
As such, their contributions would be unlikely to be perturbed by the solvent-mediated recrystallization. This observation is in noteworthy contrast to vibrational SFG measurements of the benzene/air interface, in which calculations and measurements suggest quadrupole effects may be significant. 10 , 11 Furthermore, SHG arising from trace impurities can similarly be excluded, as they would be present in equal quantities before and after exposure to solvent vapor.
This may be significant because enhanced or premature chondrocyte cell death may trigger subsequent events that accelerate degradation of cartilage.( 17 ) It was shown in articular chondrocytes that TNF-α-induced apoptosis was associated with increased expression of genes related to matrix degradation such as MMP and macr
In such cases, the role of superimposed myocarditis in the course of the disease may be significant.
Moreover, this feature is shared with some plant species [ 164 ] and may be significant in terms of ribosome biogenesis and cellular efficiency.
Given the fact that ChrY is a small, often mutated chromosome in cancer [ 58 ] several identified ChrY-encoded antigenic regions whose loss or alteration may be significant to this process due to the potential to induce camouflaging.
We speculated that this evidence may be significant since ASD individuals, unlike PWS individuals, do not have hypothalamic syndrome, which can per se cause temperature fluctuations and sensory abnormalities.
As mentioned above, this hypothesis has been invalidated for human plague and may be significant only in highly susceptible rodent populations experiencing a high flea burden [ 3 , 4 , 50 ].
[ 40 ] offer further support about the central role of NO in root-pathogen interaction, which may be significant to developing novel plant-protection strategies [ 46 ].
Despite the advantages, nMS is not used to the extent of the more common biophysical methods, including those where there may be significant challenges such as X-ray crystallography, that requires proteins suitable for crystallisation, or NMR, where proteins are commonly isotopically labelled and high fragment stock concentrations are needed, that can frequently meet with insufficient solubility leaving many fragments unsuitable.
Thus, there may be significant prognostic importance to measuring adipokines.
145 6.8 Alternative ways of regulating gene expression in AD There are alternatives that may be significant in causing large‐scale changes in gene expression in addition to the general disruption of nuclear/cytoplasmic trafficking indicated here.
It may be significant that no living cell today has an intracellular concentration of 0.6 M NaCl.
Its proposed evaluation methods are based on the detection of attributes that may be significant in different degrees of impairment.
Although we cannot be certain that in a large study the difference in serious adverse events may be significant, we think this is unlikely because previous systematic reviews of combination DMARD therapies[35] and treat to target trials [8] showed no increases in adverse events in many of these trials.
This suggests that there may be significant changes in RNA unrelated to the growth rate.
Our study suggests that open human defecation that takes place in the immediate surroundings of homes that raise free-ranging pigs may be significant sources of exposure to T . solium eggs and important routes of transmission to be considered in future control efforts.
The second review article by Vonhoff and Keshishian discusses how during the development of neuromuscular connections in the fruit fly an interaction between the glutamatergic type I terminals of motoneurons and octopaminergic type II terminals of neuromodulatory neurons may be significant.
Additionally, gene expression in processes such as PLD may be significant, but additive or mildly synergistic in nature ( Figure 3—figure supplement 2 ), and thus may play a role in the non-synergistic outcomes of correlated monotherapies.
Concussion-Like Symptoms Across a multitude of studies ( 30 – 32 ), it has become evident that there may be significant overlap in daily variations of concussion-like symptoms with those experienced by an injured population.
This may be significant for the operational interpretation of results, considering that African Anopheles typically bite at night.