“may be significant”

In our study reported here, the NLR increase in 15 of 29 (52%) patients given dapsone compared with 21 of 30 (70%) patients not given dapsone may be significant.

Our findings may be significant for preventing diseases and improving health, furthermore, reducing people’s financial burden on healthcare.

In fact, side scattering may be significant and PTIs seem not to offer any protection against this.

This finding may be significant in limiting the use of synthetic antibiotics in animal husbandry and reducing the emergence of bacterial multidrug resistance.

However, the relationship between TRPS1 genotype and phenotype is not entirely consistent, and even among carriers of the same gene mutation, there may be significant differences in phenotype.

Therefore, although the emissions are low, the disease burden may be significant from a public health perspective. 11 The results of Korean studies on health effects caused by incinerators remain controversial; the results differ by the type of incinerator and materials emitted.

The results showed that there may be significant differences between peripheral RPE cells and macular RPE cells in proton transmembrane transport, endoplasmic reticulum (ER) stress and ATP metabolic processes.

This acidifying action may be significant and long lasting, and is therefore the basis for chronic disease; (c) The degranulation of mast cells and basophils, caused by the stimulus, the basis of the acute allergic response [ 77 , 78 , 80 , 84 , 138 ], as described above in Figure 1 .

This may be significant, because vitamin A is metabolized to a substance called retinoic acid.

The estimated carrier frequency of FMO3 pathogenic variants in a British Caucasian population is 0.5% to 1% although there may be significant variation in carrier status in different ethnic groups. 4 , 14 To date, the genetic profile of the Irish individuals affected with TMAU and the severity of their clinical expression has not been studied.

Further, diabetes and obesity may be significant confounding factors in terms of disease control.

And it may be significant.

These may be significant findings in view of the increasing incidence of obesity.

However, their cumulative effects may be significant.

Finally, due to the limitations of convenience sampling, there may be significant differences in gender distribution within our study.

Since the AKR inhibitor 5β-cholanic acid is a well-tolerated naturally occurring bile acid in humans, and since flufenamic acid has been used in clinical trials with manageable toxicities [ 41 ], there may be significant value in conducting clinical trials in which either 5β-cholanic acid or flufenamic acid are co-administered with doxorubicin during chemotherapy.

The effects of switchgrass cultivation on CH 4 emissions may be significant but are often ignored.

The PPI network analysis revealed that IL-1B, PTGS2, IL-8, and nMMP-9 may be significant targets for EU's effectiveness in the treatment of AS.

There may be significant differences in physical and chemical properties of plant fibers of different kinds, different producing areas, and different processing methods, thus affecting the performance of the final composites [ 40 ].

By analyzing the mediatory effects of CRP, IL-6, IL-8, and the CALLY index, it was shown that these inflammatory mediators may be significant contributors to the poor prognosis observed in NMIBC patients.

Evaluation of TME The difference in prognosis suggests that there may be significant heterogeneity between our necroptosis-related clusters, so we first scored the necroptosis of the three clusters through “ssGSEA”, which depicted that cluster 1 had the highest score, cluster 3 the second-highest, and cluster 2 the lowest ( Figure 3A ).

With considerable differences in tumor biology between adult and pediatric cancers, there may be significant differences in the presence, function and behavior of TSC in pediatric malignancies.

First, the specificity of cell types should be clarified, as there may be significant differences in the sensitivity of different cell types to DOX and the regulatory mechanisms of mitophagy.

We hypothesized that there may be significant differences in some genetic polymorphisms between the two ethnic groups [ 40 - 44 ].

A number of studies have previously estimated the time to perform remote and in-person device checks, yielding a wide range of time estimates, suggesting that there may be significant clinic-to-clinic variability [ 14 , 31 - 33 ].