The biochemical mechanisms of extension of fatty acyl chains is dependent on chain length ( 11 ) and in this context it might be significant that in preliminary experiments, we have found NAT associated with the cell membrane fraction under certain growth conditions.
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p=0.065p=0.54
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High expression of Prkcb , although not unique to PLs, might be significant in view of the role of protein kinase C β in survival signaling via NF-κB and the finding that inhibitors of protein kinase C β induce cell death in lymphomas with dysregulated expression of the gene ( 73 ).
PD-1 acts as an important negative regulator of T cell responses ( 31 ), and it might be significant that this molecule is induced after in vivo treatment with 1018 ISS on TLR-9 + PDCs in the airways.
The increased levels of circulating MCP-1 might be significant for the exacerbated lesion development in αGalCer-treated mice, since this chemokine has important proatherogenic effects ( 21 , 22 ).
The fact that lung mDCs and pDCs take up fluorescent OVA does not imply that both cells provide an identical TCR ligand density, as there might be significant differences in antigen processing and presentation efficiency ( 32 ).
The resting potential with the K-free internal solutions was in the vicinity of zero, so it seemed possible that there might be significant K entry before the axon was clamped to the holding potential.
Also, it predicts well that steady-state inactivation and steady-state exchange current have the same sodium dependence. From this experiment and from three others, however, one deviation of the results from the simple model might be significant.
Although the height distributions were similar for the contrasting stimuli, the total chi square statistic revealed a significant difference between the two at the 5% level. The presence of a significant chi square for two of the seven cells studied is an improbable event for the hypothesis tested and suggests that if more experiments were performed the total chi square might be significant at the 5% level.
Given that OEYCs influence the way public services for children are offered, there might be significant implications for the gap between the information haves and have-nots.
Also, some effect sizes might be significant in one study but not the other; meta-analysis can discard these inconsistent effect sizes which may be caused by the uniqueness of samples in that study.
While the adjusted effect of screening epoch on survival was not significant, it is suggestive – it might be significant if the tumour series was larger.
In addition to its peroxidase activity, peroxiredoxin 6 also has phospholipase A2 activity that might be significant in the brain, which has a high lipid content [ 9 ].
Even where anticoagulants are prescribed there might be significant drop out rate.
Overall, these findings allow for the possibility that the role of ZAP-70 as an adapter might be significant only in the context of a catalytically active protein kinase.
It might be significant that the breakpoints in MCF7 occur in and/or truncate BCAS1, possibly explaining its total lack of expression in MCF7 cells despite being amplified [ 27 ].
When both nuclei could be tracked in the VZ for longer than 100 min (9 of 18), we considered that the lack of entry into the neuronal layer might be significant, perhaps indicating a delayed onset of the neuronal phenotype.
The interaction of the calcium response induced by P2X7 receptors and BCR stimulation might be significant for the modulation of the immune response.
We speculate that if larger numbers could be recruited, then differences in outcomes among the three groups, such as survival rate, might be significant.
First, the three-factor design employed here de-emphasizes genes that might be significant when oxygen availability is not considered.
These dynamic changes implied that the phosphorylation of TCTP from 2.5 hr to 4 hr might be significant to guarantee this process running smoothly.
To conclude, islands, including the West Indies, might be significant sources of biodiversity for continents, and we emphasize the importance of considering reverse colonisation for interpreting biogeographic patterns.
If ovaries are more developed at biting time during the cold season, and if the mosquitoes take even more time to seek their hosts, it means that the time elapsed from oviposition to biting might be significant during such a season.
In this context, it might be significant that apart from the shared binding affinity of CRP1, CRP2 and CRP3/MLP to zyxin and α-actinin, we and others have isolated proteins specifically interacting with individual CRPs [ 33 , 8 , 34 , 10 ].
Although we did not find a significant association between these seven ADH4 variants and AD or DD in AAs in our previous studies, in view of the power variance of association methods and the population-specificity of associations, we did not exclude the possibility that these associations might be significant if adequate statistical power were available, or that other markers might be associated with these phenotypes in this population [ 6 , 7 ].
To investigate genes that might be significant in the co-occurrence of BC and BII, the central genes for the overlapping DEGs were pinpointed with the aid of CytoHubba.