64 The UKBB demonstrates only 1 moderately significant phenotypic association for pLoF variants (mean corpuscular volume) ( https://app.genebass.org/gene/ENSG00000108055 ). 65 Intriguingly, in an analysis of >31,000 individuals with neurodevelopmental phenotypes and their family members, de novo variants in SMC3 were found to be associated with developmental delay (false discovery rate = 3.46E−7), although driven mostly by missense variants. 66 The lack of phenotypic associations with SMC3 pLoF variants in large cohorts could be because of a lack of true association and/or lack of power owing to the rarity of these variants.
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“moderately significant”
Sighted at
P<0.11p>0.11
In the literature
3 ) shows that females were significantly more in category F than expected and significantly less in category B with moderately significant relationship strength.
CONCLUSIONS Nontubercular respiratory disease patients suffer from poor periodontal health status indicated by greater mean PI (moderately significant) and significantly higher mean CALs than PD patients representing a past episode of periodontitis that had caused loss of CALs and consequently gingival recession in such patients.
Results indicated moderately significant differentiation between the Northern Ireland populations and those in the Isle of Man and Wales.
Factor loading values well above 0.40 are moderately significant, and 0.50 are extremely significant [ 106 ].
Thus, for Active genes we found: strongly significant negative CC for resistant nucleosomal sites around TSS [−120; +80] for tissue-specific and modest; moderate negative CC for sensitive nucleosomal sites for tissue-specific [−30; +50] and modest [+10; +70]; strongly significant positive CC downstream TSS [+70; +200] for tissue-specific and modest; moderately significant positive CC for sensitive nucleosomal sites upstream TSS in tissue-specific [−210; −180]) and modest [−160; −150].
Notably, moderately significant correlations were observed between the P50/N100 slope and both STAI-T score (r = −0.32) and HA (r = −0.41), as well as between the N100/P200 slope and both STAI-T score (r = −0.40) and HA (r = −0.38) ( p < 0.05 for each).
Nevertheless, variants of Pparg and Tcf7l2 have been consistently found in recent GWA for T2DM and appear to be moderately significant in our meta-analysis as well.
Our meta-analysis demonstrated a moderately significant positive relationship (r=0.56, 95% CI (0.42, 0.71)) between insulin and leptin levels in women with PCOS.
The moderately significant are those with e-values between e-20 to e-99.
The B-2 eluate peak exhibited a moderately significant impact, with an inhibition rate of 12.4%, possibly due to the presence of consequent peaks ( Supplementary Table S4 ).
Values 0.90 < pbe < 0.94 or 0.06 < pbe < 0.10 may be considered moderately significant, 0.95 < pbe < 0.99 or 0.01 < pbe < 0.05 may be considered significant, and pbe > 0.99 or < 0.01 highly significant. 2-to-1 Matched-Pair Analysis To further evaluate the impact of PK-guided Bu dosing, we compared the outcomes of patients in the fixed-dose Bu group whose natural metabolic capacity for busulfan yielded an average daily Bu AUC of 6,000 μM-min (±10%) when they received 130 mg/m 2 with patients in the PK-guided Bu dose group using a matched-pair analysis.
The post-exposure results for the O 3 exposure show that 5/7 cytokines have Post/Pre ratios that are below “1”, with IL-2 having a significant decrease and IL-5, IFN-γ, and TNF-α having moderately significant decreases (see Fig 3 ).
Identified clusters were classified as primary clusters (highest LLR, p < 0.01) representing the most significant risk areas, and secondary clusters (high LLR, p < 0.05) representing moderately significant risk areas [ 14 ].
Mean SBP and GGT were significantly elevated in those exposed to military environments, with a moderately significant association existing between blood lead levels (BLLs) and SBP.
coli was not significant after short incubation times (1 h) and it was moderately significant (30–45%) in the case of S. aureus only with large concentrations of materials (MIC × 10).
Furthermore, there is a moderately significant negative correlation between nurses’ active procrastination behavior and their passive procrastination behavior.
Although the Pearson correlation coefficient associations were slightly and moderately significant amongst the SPEQ, PSQ, and second-order four-factor model of the PPES, the significance exists and is statistically meaningful [ 28 , 30 ].
That there is only a moderately significant linear relationship between metastatic potential and C9-Met-DNA copy number suggests that, although the presence of C9-Met-DNA is essential, it may not necessarily be sufficient for the transfected Rama 37 cell to become metastatic in vivo .
Since the FFB-Mot showed moderately significant associations with fitness batteries in prior research, the use of self-reported questionnaires such as the FFB-Mot may be a simple and cost-effective way of assessing fitness in research studies.
The saturated NHC complex 1 bearing the cyclohexyl substituent at the nitrogen atom exhibited the highest ethane conversion (acetic acid yield of 40%) while the effect of different ring size substituent of complexes 1 and 4 was moderately significant (15% yield decrease from a C 6 to C 12 ring, Figure 2 ).
Suggestive significance for P-value 0.05<P<0.10, moderately significant for P-value 0.01<P £ 0.05, and strongly significant for P-value P£0.01.
In those cases where there were differences between the relationships in HER2+ and HER2−, the p values were only ever moderately significant.
The genomic patterns of H4K5ac and H4K8ac were comparable (Figure S15c, d ) and showed a moderately significant connection with gene transcription (Figure S15e ).
A P ‐value of < 0.05, < 0.01, and < 0.001 was considered to denote significant, moderately significant, and highly significant differences, respectively.