Barely Significant
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“narrowly missed statistical significance”

228 sentences · 228 papers · 276 search hits before verification

In the literature

Valproate dose and teratogenic risk Data from the Israeli Teratology Information Service database[ 5 ] suggested that teratogenicity with valproate was more likely at doses of 1000 mg/day or higher; the risk was 21.9% with valproate but just 2.5% in controls.[ 5 ] Data from the Australian Pregnancy Registry also indicated that the risk was greater in patients who used doses of 1100 mg/day and higher.[ 6 ] Data from the North American Antiepileptic Drug Pregnancy Registry found that the trend for valproate to exert a dose-dependent risk narrowly missed statistical significance.[ 8 ] 6.
Teratogenicity and hyperprolactinemia.
Indian J Psychiatry · 2009 · PMC2738408
5 In terms of clinical outcomes, two moderately sized randomized trials published prior to HEART‐FID (Ferric Carboxymaltose in Heart Failure with Iron Deficiency) demonstrated a reduction in HF hospitalizations and cardiovascular deaths in both hospitalized and stable patients which narrowly missed statistical significance. 6 , 7 The HEART‐FID trial further substantiated these results; thus, consideration of iron replacement in eligible patients with HF and ID is warranted. 8 , 9 The efficacy and safety of intravenous ferric carboxymaltose (FCM) has previously been demonstrated in multiple disease states (e.g. chronic kidney disease [CKD], inflammatory bowel disease, heavy uterine bleeding, postpartum period) including HF. 7 , 10 , 11 Prior studies with FCM have shown transient, asymptomatic hypophosphataemia.