Like the liberal regression for AUC, there were no regressors among the individual parameters for heterogeneity in the mean difference in contrast between the groups; however, analyzing the grouped parameters with principal component analysis revealed moderators in the primary principal components across all the parameters and near significance for parameters moderating the exchange rate tuning of APTw contrast.
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The association with oestrogen receptor status showed near significance (Table 3 ).
Although such association was not seen in men, it was near significance level (OR, 0.69; 95% CI, 0.44-1.07; P trend = 0.05).
We found several associations in important gene sets that were near significance in this study, particularly in genes near GWAS peaks (Supplementary Data 3 , Supplementary Fig. 7 ).
Moreover, binding ELISA assay demonstrated epitope-decreasing immunization induced higher IgG titer against the conserved EDIII domain compared to repeated immunization ( Figure 1C ) with near significance.
Furthermore, PVE cases showed higher rates of 30-day mortality compared with NVE with near significance, which is likely multifactorial.
Multivariate analysis of prognostic factors for OS included all variables that demonstrated statistical significance or near significance in the univariate analysis.
Although the difference between TL and nTL based on the Day 1 recordings was not significant, the near significance may warrant further study with a larger sample size.
However, although there were fewer participants, the result for the younger group was near significance.
This transformation might have influenced the detection of certain QTLs near significance threshold.
The significant association between amyloid‐PGS and A+, and near significance after adding the APOE score, demonstrates the existence of additional genetic effects outside of APOE that have an impact on amyloid accumulation.
Finally, multiple tests increase the risk of Type I error [ 29 ]; findings near significance should be interpreted cautiously.
As above, we attribute the near significance of this analysis to slightly under-powering our n ’s.
In the fully adjusted Model 5, caregiver-reported societal cultural stress was the only stressor independently associated with a higher hazard of lifetime BD onset (HR, 2.15; 95% CI, 1.18–3.89), while the effect of marijuana use was near significance (HR, 1.90, 95% CI, 1.00–3.63, p, 0.051).
As for plasma allopurinol-riboside concentrations, we also observed intergenic variants that showed near significance close to NXPH1 .
The models with the linear covariate TCM adjustment yielded similar significant effects and interactions (i.e., age and sex effects and their interactions with and without TCM) to the allometric models: The linear covariate model underestimated or overestimated effects in 2.35% (102/4340) of statistical tests and these differences occurred in regions near significance with small effect sizes ( Supplemental Figures File 3 and 4 , https://osf.io/s4qc5/ ).
These results were specific and not influenced by other cognitive functions such as global cognition, memory, language comprehension, and non-verbal reasoning, with the exception of the selective attention task that reached a near significance level.
Although this was not found to be significant, the near significance did suggest the need for further research on the role of social work education in shaping attitudes [ 11 ].
We attribute this near significance to the collapse of many EGTA-treated spheroids prior to the 15-minute time point, both reducing sample size and complicating measurement of vacuole fluorescence.
Variables selected for binomial regression were those exhibiting significance or near significance during group comparison.
[ 21 ], although the level of significance for memory span was near significance and increasing sample size may lead to a significant difference.
Given its near significance p -value, the predictor might have achieved statistical significance in association with perceived understanding, and the plausibility for such a phenomenon to occur could be attributed to the size of our sample, which may have increased the possibility of type II error in our analysis.
However, multiple comparisons may increase the risk of false positives, and results near significance should be interpreted with caution.
Regarding factors associated with the prolonged hospital stay, major pre- and post-operative variables were analysed for the association, which revealed no significant risk factor except for the near significance of the elderly age (Table 2 ).
A significant association of FGFR1 with ER and Ki67 in the overall cohort while significant correlation with low PR and high Ki67 as well as a near significance with HER in luminal cancers were observed.