Barely Significant
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“near significance”

506 sentences · 506 papers · 894 search hits before verification · confirmed specimen

Sighted at

p=0.07

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Other genes of interest near significance included, on Chromosome 1, a Riboflavin synthase-like gene ( RboS-L ), on Chromosome 2, a Prolyl 4-hydroxylase ( P4H1 ) gene involved in hydroxyproline synthesis, on Chromosome 3, an IAA-Ala Amino Hydrolase ( IAH ) gene involved in yielding IAA from amino acid conjugates, on Chromosome 5, a Guanosine Diphosphatase1 gene ( GDA1 ) involved in transport of GDP-Mannose into the lumen of the Golgi apparatus, on Chromosome 7, a UDP-Glu:UDP-Gal 4-epimerase gene ( UGE5 ), and, on Chromosome 10, a WRKY63-like transcription factor gene (Fig. 4 , Table 3 ).
LVI (p-value = 0.050), PNI (p-value = 0.025), axillary lymph node involvement (p-value = 0.027), and Ki-67 (p-value = 0.018), index showed significant association with PTB on univariate logistic regression analysis, while only Ki-67 (p-value = 0.017) index showed significant association with PTB on multivariate logistic regression analysis, although PNI (p-value = 0.074) showed near significance.
48 An initial study of 8100 genes in 20 MPNSTs found no significant differences in expression profile based on NF1 status (10 NF1-related, 10 sporadic), although 6 genes showed a trend near significance, 3 genes were related to whether tumors were peripheral (on a limb) versus central (trunk/neck/head), and metastasis moderately correlated with expression of 12 genes. 49 The authors then examined 22 additional MPNSTs, and found a significant signature that differentiated 9 MPNSTs (8 NF1, 1 sporadic) from the others, characterized by higher expression of neuroglial and Schwann cell differentiation genes (e.g.