Direct application of recombinant IL-1β (5 ng) onto the spinal cord of naïve (nonarthritic) rats for 20 to 30 min increased spiking evoked by 10-g von Frey stimulation from 4.3 ± 2.9 to 8.2 ± 3.6 spike/s ( P < 0.05, Wilcoxon signed-rank test; n = 12 cells) and caused a nearly significant increase in spontaneous spiking from 0.3 ± 0.2 to 2.0 ± 1.3 spike/s ( P = 0.11, Wilcoxon signed-rank test), consistent with past studies ( 16 , 18 , 19 ).
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Differences in KIM-1 concentrations in particular subgroups were nearly significant ( P = 0.11).
When using baseline and post-follow-up (ie, 12 months) time points, there was a nearly significant group-by-time interaction for CRP ( P = .11).
IVIG significantly affected gastrointestinal cancers ( p = 0.0175, Table 2 ) and was nearly significant for dermatologic cancers ( p = 0.11, Table 2 ).
This results in a first-order coefficient for Qualave that is nearly significant at the 10% level ( p = 0.112).
There was a nearly significant negative correlation between zooplankton proportion in the diet and the relative gut length when silver carp were stocked in a high density ( p = 0.112).
Suppression in the Th1 modules between the baseline and maintenance time points was nearly significant ( P = 0.117), and no difference was observed for Th17 expression.
However, the head shape between males and females of the Northern clade showed a greater, nearly significant, amount of divergence (Goodall's statistics = 1.41; P = 0.12) than between males and females of the Southern clade (Goodall's statistics = 0.95; P = 0.52).
Importantly, nearly significant correlations were found between Lactobacilli versus DMFT (rmcorr = 0.241; p = 0.120), Lactobacilli counts versus BOP (rmcorr = -0.291, p = 0.058), and Lactobacilli versus Candida (rmcorr = 0.287; p = 0.062).
Univariate analysis showed age as a significant factor in surgical failure for Criterion A ( p < 0.05) and a nearly significant factor for Criterion B ( p = 0.12).
Time-weighted average of MET was again significant in the meta-regression of 5 controlled studies (Beta coefficient = 0.41, p = 0.04) and nearly significant (Beta coefficient = 0.14, p = 0.12) in the complete set of controlled studies.
4 C ), and nearly significant for target set II ( Wu et al. 2009 ) ( P- value = 0.121, r = −0.224, n = 49; fig. 4 D ) and target set III ( P- value = 0.119, r = −0.161, n = 95; supplementary fig.
A nearly significant difference in complete healing at 8 weeks (OR=1.72 [95%CI, 0.86, 3.45]; P=0.127; I2=0.0%) and the percentage of change in the area at 4 weeks (-7.1% [95%CI, -17.4, 3.3]; P=0.180; I2=0.0%) was also observed.
observed)× Stimulus interaction effect (F (2,18) = 5.14; P = 0.014, ε = 0.56) and nearly significant Datatype × Condition × Stimulus interaction (F (10,90) = 39.00; P = 0.129, ε = 0.42), which both reached significance by taking the Attend vs.
The increased grip strength in the injured groups and the nearly significant increased power position grip strength (p=0.13) are interesting findings that are not easily explained.
For cancer of the central nervous system, a nearly significant increase of the ERR with the amount of 131 I administered was found ( P =0.13).
HFD + Veh), and showing a nearly significant trend for the other treatments ( p = 0.137 for 0.3 mg and p = 0.059 for 5.0 mg, both vs.
For the rs11978267, nearly significant weak negative correlations were observed for platelet count (R = − 0.096, P = 0.14) and LDH parameters (R = − 0.286, P = 0.18) (Table 4 ).
At day 10, the difference in collagen III expression was nearly significant ( p = 0.145), with FBs expressing 31.33 ± 1.62%, cocultures 40.60 ± 2.86%, and ECs 44.92 ± 7.92%.
Age, sex, smoking status, stage, grade, mutation status, surgical type, and adjuvant therapy were included in the multivariable model if the P value of unadjusted effect was less than 0.3 in the univariable analysis and the P value of the adjusted effect kept significant or nearly significant (P value <0.15) in the multivariable model after adjustment of multiple covariates.
To provide the reader with information describing the statistical significance of estimates that may be close to conventional levels of significance, in Tables 4 through 7 we indicate the significance of coefficient estimates that were ‘weakly significant’ (0.05 < p ≤ 0.10) and ‘nearly significant’ (0.10 < p ≤ 0.15).
Only associations that were significant in the total cohort ( p < 0.05) and nearly significant ( p < 0.15) in both countries separately were considered robust.
Similarly, stressed rats had upregulated expression of another predicted target gene, Mapk10 (adj p = 0.16, nearly significant), compared to non-stressed animals (Figure 5B ).
The age groups under 5 years (8.07%) and 55–85 years (9.52%) had the highest positivity rates, with a nearly significant trend ((χ2=6.517, p = 0.164), suggesting that age may influence infection risk.
At mean age (and after controlling for the mentioned covariates) there was a nearly significant 0.2 cm increased head circumference in individuals classified as simplex (p = 0.17) over multiplex individuals.