This observation has probable significance beyond CEBPβ alone, as other members of the basic leucine-zipper (bZIP) family of TFs would accommodate DNA cytosine methylation within their recognition sequences ( 42 ), and may thus have similar binding preferences for the T:G product of 5mC:G deamination.
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In order to study the probable significance of co-evolutionary pairings which are not occurring in close spatial proximity, we have studied co-evolution patterns in certain receptor-ligand protein hetero-dimers that are known to interact aberrantly during cancer metastasis.
Considering the statistically significant differences between the values of the ammonia levels in the patients of the compared groups, as well as probable significance of other factors in the diagnosis of IMD, we assessed the effect of the combination of factors by the method of discriminant analysis with forced inclusion of the studied factors.
Thus, we corroborated previous reports of a-granule 2 , 4 , 10 and one report of dense granule 10 deficiencies in XLTT, with probable significance for the bleeding diathesis.
5 Superficial erosion of an atherosclerotic plaque leading to thrombus formation may be the main mechanism revealed by previous studies; however, it could also be formed without tissue abnormality with a probable significance of Virchow’s triad. 5–7 European Society of Cardiology guidelines emphasize the notion of complex aortic plaques (defined as plaques with mobile thrombi or ulcerations or a thickness ≥4 mm).
For Google results, we considered as ‘hits’ only those results that originated from peer‐reviewed literature in which the SNP was described as being of probable significance to a particular phenotype.
Increasingly, a well-trained PET/CT radiologist can provide advice on the probable significance of such findings, in conjunction with the clinical context.
Regarding SRS, the number of children born following ART was small ( n = 13); therefore, probable significance for SRS incidences could not be inferred.
The probable significance of such structures for the mycoplasma cell is discussed.
Another region of probable significance is the cysteine “cluster” of C124, C127, and C129.
I would like to state here that I do not neglect the probable significance of microbiota to cancer.
Pearson correlation statistical analysis was carried out for the detection of a probable significance between two different parameters.
These five key candidate genes and their probable significance in IgAN indicated that they could be novel therapeutic target genes.
Experimental and clinical investigations have noted the possible importance of phenolic compounds as important phytochemicals in moderating upstream dysregulated OS/inflammatory signaling mediators and axonal regeneration's extrinsic pathways after the SCI probable significance of phenolic compounds as important phytochemicals in mediating upstream dysregulated OS/inflammatory signaling mediators.
Notably, miRNAs jointly control approximately 30% of the human genome, highlighting their probable significance as regulators of gene expression.
We discuss the consequences of these differential gradients and their probable significance in instigating evolutionary adaptive behavior in the wax-nest building insects to utilize the same material for two distinction and functionally different purposes.
As shown in Fig 2B , LysC knockdown led to obvious shrimp death in the absence of external infection, suggesting the probable significance of LysC for shrimp survival.
We report all results with p < 0.05 and pd > 0.97 as threshold for likely existence of effects and %ROPE < 2.5 as threshold for probable significance of the effect controlled by age and gender.
Pearson correlation statistical analysis was determined for detection of a probable significance between two different parameters.
Pearson correlation statistical analysis was performed for the detection of a probable significance between two different parameters.
This finding points to a probable significance of DCX in ECM remodeling and crosstalk between leiomyoma and myometrium in this process.
As mentioned before, from the 109 dysregulated miRNAs identified, 10 were reported across 15 studies, thus indicating a higher probable significance in terms of their applicability [ Table 2 ].[ 13 , 14 , 17 , 18 , 20 , 21 , 23 , 26 , 27 , 31 , 35 , 36 , 42 ] However, caution should be taken for qualitative synthesis, and numbers alone should be a sole comparator for its significance.
Pearson correlation statistical analysis was performed for the detection of a probable significance between two different parameters.
Candidate gene association studies It is a hypothesis-driven method in which candidate genes are chosen based on prior knowledge such as a gene's biological function, position, or probable significance about a given phenotype[ 47 ].