Principal-coordinate analysis of the weighted UniFrac distance matrix including all pre-clindamycin samples showed a trend toward separation of the C. albicans -colonized and uncolonized populations ( Fig. 1E ) (permutational multivariate analysis of variance [PERMANOVA] P = 0.055, 999 permutations).
However, sdLDL to total LDL ratio was not different between the two groups, whereas lbLDL percentage showed a trend towards higher values FH group compared to controls (p = 0.055) (Table 2 ).
DACH1 positivity was associated with good survival in patients treated with tamoxifen (χ 2 = 8.30, p = 0.004) and in addition, also showed a trend in patients not receiving tamoxifen (χ 2 = 3.7, p = 0.055).
In subgroup analyses, in ER + /PR + /HER2 − , lower UNC5A H score showed a trend of poor overall survival ( p = 0.055) (Fig. 2c ).
Motor symptoms measured by UPDRS only showed a trend to be worse in PD OFF than PD ON [ t (23) = −2.0, p = 0.055], and pegboard performance for the more affected side was significantly worse for PD OFF than PD ON [ t (23) = −2.61, p < 0.05] but not for the less affected side.
There was no significant difference as regards gender, ethnicity, age and baseline immune-virological status between the two groups although females showed a trend towards a higher frequency of NVP-induced hepatotoxicity (75.0% vs 35.9%; p = 0.055).
Post hoc comparison revealed a significant increase in the RC slope ( p = 0.006; Figure 4 ), whereas the change in rMT was not significant but showed a trend toward reduction ( p = 0.055) after rPNMS ( Figure 5 ).
Within this, endpoint voxel assessment of GABA+ data was possible in 5/11 simvastatin and 9/15 placebo and showed a trend towards between-group increase in the simvastatin group compared to placebo (mean 1.82 placebo vs. 2.39 simvastatin ( t (12) = − 2.12, p = .055, two-tailed uncorrected), although this was not present when adjusted for baseline values (ANCOVA p = 0.188, Mann-Whitney p = 0.66; Fig. 3 a).
6.9 ± 0.2 mmol/l, P = 0.002) and showed a trend to be significantly different from the BIC-induced increase in plasma glucose in the vehicle group ( P = 0.055).
Pairwise DeLong comparisons of M4A, M4B, and M4C revealed no statistically significant differences in AUC between the three nutritional models (all p > 0.05), although the comparison of M4A versus M4C showed a trend favouring CONUT (ΔAUC = 0.077, p = 0.055; Supplementary Table S4 ).
These showed a trend-level reduction in NAA in AnxDs ( g = −0.47, 95% CI = +0.01 to −0.95, p = 0.055).
PD-L1 expression significantly correlated with serum CK levels ( r = 0.442, P = 0.038) and MMT-8 score ( r = − 0.415, P = 0.049), and showed a trend toward significant correlation with CTCAE grade ( r = 0.407, P = 0.055).
After exclusion of this observation, the association no longer reached significance but rather showed a trend-level effect (Spearman r = 0.473, p = 0.055).
After adjustment for age and left atrial volume, the intervention group showed a trend toward improved AF‐free survival (adjusted hazard ratio [HR] 0.491, 95% CI 0.237–1.016, p = 0.055).
For WC a significant increase was found in males (1.6 cm; p <0.001), while females showed a trend towards a significant increase (0.6 cm; p = 0.055) between year 4 and 5 (T4-T5).
Unlike nitrate, nitrite did not show any significant associations with MetS including HOMA-IR, BMI, GGT, CRP, leukocyte count, triglycerides or ALT, but correlated inversely with vegetable intake (r = −0.34, p = 0.037) and showed a trend with TFT (r = 0.31, p = 0.055). 3.2.
The interaction showed a trend on GN – mean RT go responses (F (1, 99) = 3.77, p = .055, Fig. 3 E).
The duct-to-duct biliary anastomosis and pre-transplant CMV IgG seropositivity showed a trend toward higher risk ( p = 0.055 and p = 0.088, respectively).
Patients who were older at diagnosis also showed a trend in being associated with a higher mortality ( p = 0.055). 2.3.
Finally, in the multivariate analysis of Global Adaptive Functioning (GAF), Social Problems showed a trend-level negative association (B = −0.71, p = 0.055), consistent with the pattern observed in the univariate model, but not reaching conventional statistical significance ( Table 5 ).
Urodilatin release capacity during the second hour of NMP was negatively correlated with the duration of DGF, and it showed a trend toward a negative correlation in the first hour (first hour: R s = –0.45, p = 0.055; second hour: R s = –0.61, p = 0.0041; Table 3 ; Figure 5 ).
Home (vs nursing-home) residence showed a trend for higher odds of 30-day hospital admission (OR 1.51, 95% CI 0.99–2.32; p = 0.055).
In contrast, at time point T1, while we found no differences in entries and time spent in the open arms (panel G, two‐tailed Mann–Whitney test, U = 26, p = 0.1970 and panel H, two‐tailed Mann–Whitney test, U = 33, p = 0.5289), finasteride‐treated rats showed a trend toward more entries to the closed arms (Figure 7K , two‐tailed Mann–Whitney test, U = 14, p = 0.055), suggesting a preference to less anxiogenic component of the maze.
Age was controlled as a covariate of no-interest in all analyses because the corresponding sex difference showed a trend to significance ( t (100) = 1.944, p = 0.055) and the P3/LPP magnitude is known to decrease with age [ 100 , 101 ], which was also seen in our study ( r = − 0.401, p < 0.001***; Fig. 1 b).
Similar to PFS, histologic grade significantly impacted OS in univariate analysis (p=0.012) and showed a trend in multivariate analysis (p=0.055).