Diagnostic plots from initial modeling steps showed a trend towards a decrease in the apparent central volume of distribution (V c /F) with increasing dose, indicating that saturable (i.e., capacity-limited) binding might be the underlying process.
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In the literature
[ 34 ] found no association between EGF +61 G/A and gastric cancer but that EGF +61 A/A genotype showed a trend of protection by research on 202 patients and 454 healthy controls.
Forest plot analysis of Pittsburgh sleep quality index at short- and mid-term follow-up showed a trend in favour of aquatic therapy, although not statistically significant, with weighted mean difference (WMD) = -1.71 (95% CI: -4.17 to -0.75, p = 0.17).
The values in the captopril group showed a trend.
Heart rate showed a trend to increase from on average 74 ± 20 to 94 ± 22 minutes -1 (Table 1 ).
In the DT group, the symptom scale showed a trend toward statistical significance in anxiety.
The main effect of configurations (F(1,12) = 3.552, p = 0.084) was not significant but showed a trend towards more accurate responses for repeated displays.
Although statistical significance was not proven, patients who received intravenous cyclophosphamide showed a trend towards better outcome in the recurrences of their gastrointestinal syndrome.
[ 14 ] showed a trend between APRIL levels and anti-dsDNA Ab levels and a correlation with the British Isles Lupus Assessment Group (BILAG) index score of musculoskeletal disease.
Even though the prednisone- and combination-treated groups showed a trend toward a decrease in serum CK levels, these changes were not statistically significant.
Four studies showed a trend toward a benefit from statins although not reaching statistical significance [ 65 - 68 ].
Analysis of liver sphingolipids showed a trend toward increased GL1 and GL2 in DIO mice compared to their lean counterparts, but overall there were no dramatic differences, and ceramide levels were unchanged.
2 D ); mRNA expression of G6Pase in PACAP-38 showed a trend toward an increase in comparison with vehicle ( Fig. 2 E ).
Indeed, results from our preliminary in vivo intraperitoneal glucose tolerance tests in mice only showed a trend toward KB-R7943 lowering blood glucose (data not shown).
Second, in medicated children raised interleukin levels showed a trend to normalisation.
Results Analysis of time characteristics of grain production in China Time series changes in total grain production The overall grain production (2000–2020) showed a trend of first decreasing and then increasing.
Image analysis showed a trend for an increase of the Na v 1.7 immunoreactive % area in the painful pulp group, but this was not statistically significant.
For example, homeostasis model assessment of insulin resistance and insulin levels showed a trend toward more improvement in patients undergoing LRYGB and omentectomy.
In other words, post-SARS years showed a trend toward reduced influenza-associated mortality while vaccines were mismatched.
Subsequent to this, a randomized placebo-controlled trial of subcutaneous LMWH in adults 81 showed a trend for better outcome in the treated group, but the mortality was lower in this series and there were more patients with milder presentations in the placebo arm.
In our previous study [ 16 ], the emission bands recorded up to maximum annealing temperature of 700 °C showed a trend of decreasing PL intensity with increasing temperature and the observations were understood on the basis of the various processes such as self-trapped excitons recombination which is a combined effect of defect centres generated from oxygen vacancies and particle size variation.
The pilot biopsy experiment showed a trend of larger volumes and larger cell counts obtained from the aligned nanofiber devices among a series of biopsy samples in both GBM models.
Instead, they showed a trend towards an increase in cAMP levels (Fig. 2A ).
CHOP protein expression in the LIR group and the saline-pretreated group showed a trend of upregulation compared to that of the control group.
After 72 h of co-culture, HFOs showed a trend to increased gene expression levels of the brush border gene IAP ( Figures 6 E and 6F) in both proximal and distal SI HFOs.