“showed a trend”

While analysis of data using the 3-criteria frailty index showed a trend toward association with complications, it nevertheless has potential for application in clinical practice ( Figure 1 ).

In the present study, VEGF, a driving angiogenic factor, showed a trend to reduced transcript levels.

After 12 h of treatment with 0.2 μM of LLL12, SCCF2 showed a trend towards increased caspase 3/7 activity (data not shown), but this difference did not reach statistical significance until 24 h of treatment.

A second independent ER+ breast cancer cell line, MDAMB361, showed a trend to being more de-compact than HMLE but this difference was not significant (Fig. 6a ).

A 6-year longitudinal cohort of Australian primary schoolchildren showed a trend for obesity to increase in the mid socioeconomic status group over the 6 years from 2007 to 2012 [ 39 ].

37 The Secondary Prevention of Small Subcortical Strokes (SPS3) trial, aside from studying the effect of dual-antiplatelet therapy, also examined the role of strict vs standard blood pressure management (systolic, <130 mmHg vs 130–149 mmHg) on the outcome of stroke recurrence and showed a trend toward benefit in stroke recurrence in the lower blood pressure group. 38 Current American Heart Association guidelines recommend blood pressure goals of, <140 mmHg and diastolic, 90 mmHg; however, there is evidence that the benefit of lowering blood pressure extends to levels far below this cutoff, and as suggested in the PROGRESS trial, treatment should not be reserved for only those with history of hypertension. 6 , 39 Hyperlipidemia Hypercholesterolemia is another general target in secondary stroke prevention.

These genes showed a trend of down-regulation in the PTPRG-expressing clones (Figure 5A ) and in the Akt knockdown HONE1 and HK1 cells (Figure 5B ).

Furthermore, tumor infiltrating lymphocytes surrounding CD70 + tumor cells, showed a trend towards increasing FOXP3 expression and higher CD4/CD8 ratios.

Patient characteristics Data on mortality by age were included in 15/89 patient series for 3,879 patients ( Table 2 ) and showed a trend towards increasing mortality with age.

Although SERPINE2 showed a trend toward a higher expression in cumulus cells of oocytes developing into good embryos than in cumulus cells of oocytes developing into poor embryos (Fig. 4 ), the difference was not significant between the two groups.

Insulin levels showed a trend to a non-significant decrease.

Results showed that at T0 all patients and controls presented similar MN frequencies, at T12 (12 weeks after the administration of treatments), both “acitretin + NBUVB” and “acitretin + PUVA” showed a trend towards an increase in MN frequency; however, only “acitretin + PUVA” reached a significant higher MN frequency.

5 , 42 In our work, the inclusion of high-throughput mutational status ousted IgVH from the group of independent predictors, though it showed a trend for a shorter TTFT.

In a logistic regression, bacteremia showed a trend toward an association with increased mortality (odds ratio 1.56, 95 % confidence interval 0.93 to 2.61).

Analysis of switched memory B cells in treated patients showed a trend similar to that of total memory B cells 2 years after GT (unpublished results).

Our study showed that the mean age of the evening type subjects, identified by the cluster analysis, was lower than that in the other groups, which is consistent with other studies that showed a trend for increased morningness with age [30] , even after correcting for socioeconomic and demographic factors [3,31] .

Note that 4BP-TQS also showed a trend to rescue the ACh and nicotine effects on E173K and D197N mutant.

falciparum malaria [ 51 , 52 ] instead showed a trend towards higher incidence of malaria, a variation that may relate to differences in the impact of the O+ blood group type upon severe malaria rather than the actual susceptibility to malaria.

Analysis in fixed sections from 5–6 individuals for each treatment group showed a trend of increased cardiomyocyte width related to oil exposure with a mean (±s.e.m.) in controls of 4.03 ± 0.05 μm and ranging from 4.16 ± 0.05 to 4.24 ± 0.05 μm across oil-exposed groups ( Fig. 4B ).

2 Although these cases showed a trend to reduce survival, the analysis is limited by the small number of cases.

Pasireotide LAR showed a trend toward higher tumor control rate at month 6, although it was statistically not significant, and was associated with a longer PFS than octreotide LAR.

In subgroup analyses, women, but not men, showed a trend toward poorer prognosis for DFS and OS in the subset of patients with IGFBP-3 methylation as compared with those without IGFBP-3 methylation (8-year DFS: 55.6% vs 71.6%, P = .3694 and 8-year OS: 55.6% vs 68.4%, P = .491, respectively; Figure 3 ) even with no statistical significance.

Interestingly, however, RAG-1 −∕− mice showed an increase in the time spent exploring the social stimulus compared to unfamiliar ones (almond and banana) and showed a trend toward a normal pattern of habituation (although the differences between the 3 exposure were not significant) suggesting a preserved function of the vomeronasal organ and an impaired activity of the main olfactory system (see Discussion).

Although there was no significant correlation between the CAI contralateral to the infarct side and 6-month functional outcome after stroke, patients with poor clinical outcome also showed a trend towards a higher CAI on the unaffected side.

For patients acquired on mCT, area under the ROC curve showed a trend to better sensitivity and specificity for early acquisitions, compared with late acquisitions (SUVmax AUC 0.92 versus 0.85, respectively).