Subjects receiving mazindol CR showed a trend of decreasing body weight as early as Day 7, and by Day 42 there was a mean weight loss for the mazindol CR group (− 1.73 kg; range − 9.6 to + 3.7) and a mean weight gain for the placebo group (1.07 kg; range − 2.0 to + 11.0).
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One week following rTMS (T2), the power of α and β showed a trend towards an increase, although this did not reach significance ( P > 0.05).
In a later study males and not females showed a trend but not a statistically significant alteration in delay discounting behavioral paradigm, which is considered to be a direct measure of impulsive choice behavior, as well as disrupted mesocorticolimbic serotonin function under Pb and PS exposure ( Weston et al., 2014 ).
Interestingly, a similar trend was observed in other mouse TB models where RZMH consistently showed a trend towards inferior results compared to RZME and/or RZM 12 .
L100I, V108I and Y181C also showed a trend toward increased cross-resistance, but when adjusted for multiple comparisons, these were no longer significant.
The present study also showed a trend towards lower retention rate with increasing distance of patient's place of residence from the Centre.
Multicolour flow cytometry showed a trend for NK cell activation in the patients (n=3) compared with age-matched healthy controls (n=3), based on higher frequency of surface activating and cytotoxic receptors.
In this study, although both vaccinated and non-vaccinated normal ewes showed a trend toward increased SCC as the study went along, the increase in SCC was far less significant in the vaccinated ewes which may indicate a significant level of protection provided by the vaccine in this group.
The graph demonstrates that more severe abnormalities in TO were significantly associated with deterioration of liver disease ( Fig 2A ) and showed a trend towards increased number of decompensating events within 6 months ( Fig 2B ).
Intriguingly, of factors in the primary tumor, increased levels of tumor-infiltrating lymphocytes showed a trend toward improved survival in patients with brain metastasis.
Older age (P=0.051) and English fluency (P=0.077) also showed a trend toward tolerability, with more patients in the 60-69 year-old age group (35.4% vs. 24.2%) than in the 50-59 year-old age group (40.4% vs. 50.9%) tolerating split-dose preparation.
Neutrophils from nonresolving donors of sepsis by day 7 (SOFA > 3, N = 9) showed a trend towards generating a lower number of NETs compared with resolvers and healthy aged controls (39347 ± 6103 versus 42545 ± 2502 versus 49659 ± 3285), but this failed to reach significance ( p = 0.17, ANOVA).
However, COL1A1 and ALPL, the specific osteoblast markers, showed a trend towards upregulation at the 5-day time point (5.92 ± 1.34-fold and 1.33 ± 0.31-fold, in FCS, resp.; 10.42 ± 4.35-fold and 1.54 ± 0.37-fold, in HAS, resp.) ( Figure 7(b) ).
However, the change in the intercellular CO 2 concentration (Ci) showed a trend opposite to that of Pn ( Figure 4E ).
Changes in the LVESV showed a trend towards an improvement in the studied groups (Fig. 6A ).
CsSAG12-1 and CsAALP also showed a trend of increased expression in response to SA treatment, although the induction was not statistically significant.
3 Our results showed a trend of increasing lung cancer incidence in women, consistent with global trends.
ARO and CMA1 gene expression levels were comparable in CP/CPPS patients and controls ( p > 0.05) (Figure 2B.2 and 2B.3 ), whereas PU.1 , although also not significantly different, showed a trend towards lower expression in patients (Figure 2B.4 ).
Specifically, both aerobic and combined aerobic and resistance exercise increased FMD by 1.21% (95% CI 0.23–2.19%) and 2.49% (95% CI 1.17–3.81%), respectively; but resistance exercise only showed a trend.
In contrast, hyaluronidase plasma levels showed a trend toward higher levels in the HES 130/0.4 group at 8 and 24 h after CLP, which did not reach statistical significance (Additional file 1 : Figure S1).
showed a trend between employment status and PCS [ 12 ].
The reperfusion amplitude also showed a trend of decline in non-responders and elevation in responders (Fig. 5h , Supplementary Fig. 9E ).
In patients with RA who underwent allogeneic HSCT, mortality was not statistically significant, but showed a trend for lower mortality rate as compared to the no IMID group.
The same group also showed that female C57BL/6 mice bearing syngeneic Panc02 pancreatic tumours and treated with sildenafil in drinking water (20 mg/kg/day) had increased survival compared to untreated mice ( P < 0.01), however male mice showed a trend towards decreased survival [ 36 ].
Our results showed a trend of improving variables in all groups.