The most recent subcohort index dates showed a trend for decreasing time to intensification, although there was a slight increase between the cohorts 1 January 2006 to 31 December 2008 and 1 January 2009 to 30 June 2011 (Figure 2 B); i.e. 46.9 and 43.1% of patients whose treatment was intensified were intensified with bolus or premix insulin, respectively, and 10.0% of individuals were intensified with GLP‐1 RAs (data not shown).
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Data from the Surveillance System of Risk and Protection Factors for Chronic Diseases by Telephone Survey (VIGITEL), between 2007 and 2013, showed a trend of reduction in the habit of ingesting alcohol and driving among adults in Brazilian state capitals and in the Federal District after legislative frameworks restricting this action 5 .
The descriptive difference even showed a trend for the opposite.
Interestingly, consistent with previous studies, lower levels of 25(OH)D showed a trend toward higher inflammatory markers in our cohort (albeit not statistically significant).
Combined exposure of endothelial cells to VEGF‐A and ANG‐1 showed a trend to reduce ANG‐2 production induced by VEGF‐A (Fig 1 D).
Subsequent 2-sample t tests for this ROI showed a trend for greater SFG activation in the MPH group compared to the placebo group ( t (25) = 2.81, P FWE = .09) at the second fMRI appointment, while no significant differences were observed at the first appointment (all P FWE > .1).
This group with slower baseline gait speed showed a trend for greater improvement in delta gait speed for pre vs. post-intervention (R 2 = 0.3906).
In the LPS-treated slices, the density of IL-1β-positive cells showed a trend for an increase soon after the LPS exposure (2–3.5 h) and increased significantly during the later periods (3.5–5.5 and 5.5–7 h) after the LPS exposure (Fig. 4b ).
There was a lower risk of definite/probable stent thrombosis with long term DAPT among patients with (0.26, 0.09 to 0.80; P=0.02) than without (1.42, 0.68 to 2.98; P=0.35) diabetes, with positive interaction testing (P=0.04 for interaction), although the landmark analysis showed a trend towards benefit in both groups.
The level of hydroxyproline showed a trend towards reduction with fluticasone and combined fluticasone and nilotinib treatment.
Within U-CLL, EZH2 high cases showed a trend for shorter TTFT compared to EZH2 low cases, though not reaching statistical significance (EZH2 high median TTFT = 1.7, EZH2 low median TTFT = 3.3 years, p = 0.14), likely due to the low number of U-CLL EZH2 low cases ( n = 18) ( Supplementary Figure 8 ) DISCUSSION We recently showed that EZH2 is overexpressed in stereotyped CLL subset #1, a paradigmatic aggressive stereotyped subset of CLL cases displaying a distinctive immune signalling profile.
As the results shown, with the increasing of BRS-3D features, the models showed a trend of increasing prediction accuracy.
Further, compared to acute plasma-derived sequences, matched DBS sequences showed a trend towards greater identity with the TF virus and lower estimates of time to MRCA ( Table 3 ).
In this study, the only gene that was significantly upregulated in CRC and showed a trend towards increased expression in CRLM was CSNK1E .
The low-density lipoprotein (LDL) showed a trend toward reduction, and the HDL increased significantly in Myo-Ins group.
Presence of macular edema showed a trend towards worse VR-QOL.
A qualitative study from England ( 13 ) showed a trend towards childless women worrying about their fertility.
Significance of this study What is already known on this subject? Our previous trial showed a trend of superiority of sequential therapy for 10 days (S10) over triple therapy for 14 days (T14) by 4.7%, but the difference was not statistically significant.
50) One recent study with 157 patients showed a trend that the majority of patients had Class II and Class III indications for ICD implantation. 48) Although the ICD implantation frequency was highest among LQT3 patients, the greatest "save" rate occurred among LQT2 women, who were assessed to be at high risk. 50) The largest study on ICD (n=233, mean
On the other hand, EE-EGCG–treated WT mice also showed a trend toward an enlargement of VGAT puncta size in CA1 (data not shown; Table 6 ), leading to a decreased VGLUT1/VGAT percentage of area occupied ( Fig. 6 D ; Table 6 ) in comparison to untreated WT mice.
During the experimental period, D group showed a decrease in the body weight whereas C, C+CM and D+CM groups showed a trend of increase in body weight.
The fluorescence of GFP driven by wild-type promoters and the activated riboswitch element showed a trend similar to the SDS-PAGE analysis of GFP expression (Fig. 4 b).
2 , 6 , 9 , 10 , 23 In a recent prospective, randomized phase II study comparing cTACE with DEBDOX TACE, the DEBDOX TACE group showed a trend for a higher objective response rate than the cTACE group (51.6% versus 43.5%, respectively), together with better tolerability. 8 , 24 In another prospective, randomized study, DEBDOX TACE resulted in a better objective response than bland embolization with non-loaded bead (73.1% versus 55.9%, res
Furthermore, spectral analysis revealed a significant increase in myogenic related component (35.4 ± 1.5 vs 30.1 ± 0.7 %, p<0.01 vs T 0 ), while NO-dependent endothelial-related component showed a trend to decrease (9.4 ± 0.9 vs 10.3 ± 0.7) ( Figure 3 ).
At 6 months and 1 year follow-up, there was no statistically significant difference among groups regarding freedom from pulsed-steroid therapy, biopsy-confirmed rejection and infection requiring hospitalization, although group A showed a trend toward better freedom from pulsed-steroid therapy and biopsy-confirmed rejection than the other 2 groups ( Table 5; Table S1, SDC, http://links.lww.com/TP/B222 ).