However, low microvessel density showed a trend towards better response rate in the docetaxel arm (RR 68% vs 40%, Table 2 ).
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The progression free survival (PFS) and the overall survival (OS) showed a trend in favor of arm A, but did not meet the statistical significance.
The MVP regimen showed a trend towards a higher response rate than the other regimens in certain trials with no benefit on survival ( Ruckdeschel et al , 1985 ).
Fiber size distribution was also analyzed in the gastrocnemius muscles and showed a trend toward reduced fiber size variability that did not reach statistical significance ( Figures S5 E and S5E′).
Any degree of uPA–PAI-1 complex accumulation inside the tumour cells showed a trend towards a significant association with nodal metastasis.
The latency to drowsiness decreased significantly after sleep deprivation, and the latency to SWS showed a trend toward a decrease (Fig. 4B ).
In the spatial distribution vector map, the reported incidence of hepatitis B showed a trend of spatial aggregation.
Conclusion Generally the results showed a trend of increase in mosquito resistance status with cross-resistance against all the three pyrethroid insecticides.
In contrast, mice that received ATL-801 did not lose body weight and showed a trend towards recovery of their body weight.
Fractional shortening showed a trend towards reduction ( Fig. 2K ).
Injury significantly decreased nicotinamide adenine dinucleotide phosphate staining and FK1706 treatment showed a trend toward increased staining [ 81 , 82 ]. 5.3.
Interestingly, garlic-only intervention arms of reviewed studies which were not suitable for meta-analysis also showed a trend for greater reduction in BP with higher starting BP.
More importantly, the TORCH study also supported the safety of LABAs in individuals with COPD, and showed a trend towards increased survival for patients treated with salmeterol alone compared with placebo (hazard ratio 0.879, 95% CI 0.729–1.061) and no increase in adverse events ( 93 ).
In the first experiment, tadpoles with resistant haplotypes ( f and j ), but not those with a susceptible haplotype ( g ), showed a trend of reduced growth when exposed to the pathogen, which suggests a possible tradeoff between growth and immune function.
MYH2 expression did not differ significantly between the groups but the EG showed a trend towards lower expression levels (Additional file 2 ).
dysgalactiae infections showed a trend towards longer severe and moderate symptom duration.
When subjects with metabolic syndrome and with diabetes were compared with those without diabetes, those with diabetes showed a trend toward a lower prevalence of abnormal HDL (50.1% vs. 62.8% in those subjects with metabolic syndrome without diabetes) and triglycerides (59.3% vs. 65.9%).
They also showed a trend toward higher ΔAUC insulin .
On the other hand, a substantial change was noted for the laser group between pretreatment and two weeks posttreatment.The microbial levels in all groups showed a trend of fluctuation over the next weeks after treatment, although there were no statistically significant differences ( P > 0.05) Table 3 and Fig. 1 .
Atrial tachyarrhythmias also showed a trend toward reduction, while hospital admission for myocardial infarction showed a trend toward reduction in CHARM Added and CHARM Preserved. ‘Other’ cardiovascular admissions were fewer in the candesartan group in CHARM Alternative and CHARM-Added, and just nominally greater in the candesartan group in CHARM-Preserved.
The phase III study of pazopanib as maintenance treatment, despite its early termination, showed a trend toward improved PFS.
CATB, CATL, uPA and PAI-1 showed a trend towards increase in patients with UC compared with controls, but the differences were statistically not significant (Table 1 ).
The liver enzymes did not increase in response to treatment, but showed a trend towards normalization (reduction) as clinical symptoms improved (data not shown).
The incidence of rod fractures showed a trend similar to that of PJK and PJF.
In addition, the genes in this cluster also showed a trend of down-regulation in hyphae which suggested that, unlike the 244 up-regulated genes, decreases in the mRNA levels of this cluster of genes was not specific for conidia.