Notably, even in the subgroup of those patients with “favourable” characteristics (those with ECOG 0, normal LDH, and no M1c disease), starting with nivolumab and ipilimumab showed a trend for improved OS (86.2 vs. 54.1 months p = 0.059).
In the present study, we showed a trend toward increased expression of CEACAM-1 and CD155 on tumor cells after anti-PD-1 therapy in patients with unresectable advanced or recurrent G/GEJ cancer ( p = 0.059 and p = 0.093, respectively) ( Figure 5 g,h).
Associated Factors of GDF-15 In the univariable linear regression analysis, SOFA score and serum lactate level had a positive correlation with GDF-15 level (both p < 0.001) and APACHE II score showed a trend of a positive correlation with GDF-15 ( p = 0.059, Table 4 ).
In the case of detour latencies, the CI also showed a trend-like interaction with the number of closed door trials before the first open door trial (LR test: χ 2 (2) = 5.668; p = 0.059).
The interaction showed a trend (F(1,26) = 3.917, p = 0.059).
Due to large variations in the cross-section area within the group of neuromas and non-affected nerves, FR and CSA showed a trend for a correlation (r = 0.453) without being significant (p = 0.059, see Fig. 7 B) while VR and CSA correlated significantly (r = 0.513, p = 0.03; see Fig. 7 C).
Nodal involvement was prognostic for poor DFS ( p = 0.022), MFS ( p = 0.044) ( Figure 4 ) and showed a trend toward impaired OS ( p = 0.059).
The number of consultations were significantly higher in the pre-implantation phase (2.1±1.8 vs 1.2±1.5, p<0.0001), and showed a trend toward significant increase in the post-implantation phase (7.8±3.7 vs 6.9±2.8, p=0.059) ( table 2 ).
When comparing each experimental group, only SC-W and WSD-LPS were significantly different ( p = 0.006), however, the results showed a trend between the two WSD groups at day 1 ( p = 0.059).
While not significant, MS alone showed a trend for increased in risk of overall cancer incidence (OR 1.25, 95% CI 1.05, 1.50, p = 0.059) ( Fig 2D ).
Post hoc tests showed a trend toward an increase of functional coupling between TP0 and TP2 ( p = .059) and a significant increase between TP0 and TP3 in L2 SJT ( p = .008; see Figure 2c ).
Analysis of the NPDR group revealed the mean age of those with IRMA showed a trend to be lower than those without (IRMA mean 56.9 years, without IRMA 60.94, p = 0.059).
Besides, TBX22 showed a trend in distinguishing between the RET fusion group and the RET wild-type group ( Figure 3D , p = 0.059).
On Day 2 of the forced swim test, one-way ANOVA showed a trend to a statistically significant difference in the latency of floating and no differences in the duration of floating or velocity ( P = 0.059, F = 2.46; P = 0.48, F = 0.89; and P = 0.40, F = 1.04, resp., Figure 4(b) ).
Furthermore, when violent/serious SA were compared to non-violent/non-serious SA and AC, the RMET neutral valence category showed a trend for group factor ( p < 0.059) and RMET scores were lower in the violent/serious SA than AC group (OR = 0.79 [0.64, 0.96]).
Dignity therapy group showed a trend towards statistical improvement in anxiety ( p = 0.059).
Similar to the findings in all 64 patients, female patients showed a trend toward longer mPFS ( p = 0.059) and mOS ( p = 0.091).
The VDD group showed a trend of a higher S2:S1 ratio than the ND group ( p = 0.059; Figure 4 D), whereas there were no group differences in EEG responses to S1 and S2 ( Figure 4 B,C).
As shown in Figure 2 B, samples positive for perivascular NRP1 showed a trend toward smaller vessel area ( p ‐value = 0.059) and a significantly smaller vessel size, compared to samples lacking NRP1 expression.
Moreover, even though not reaching statistical significance, females showed a trend of higher odds of SARSCoV- 2 positivity [adjusted OR (95% CI): 1.108 (0.996-1.232), p=0.059], when compared to males.
Correlation analysis with overall survival (OS) showed a trend toward poor prognosis in patients with higher HAMP expression (p = 0.059) (Fig. 5b ); analysis of other iron related genes did not show statistical significance.
Sobel test for significance of the mediation showed a trend, failing to reach significance ( z -score = −1.89, P = 0.059).
When we evaluated the prognostic value of isolated 8q, ERG and PTEN changes in the three risk groups defined by CAPRA-S, we found that intermediate risk patients with 8q + and high-risk patients with PTEN- showed a trend towards worse clinical outcome ( P = .059 and P = .077, respectively, Supplementary Figure 6, A and B ).
Patients with scores ≥4 showed a trend towards more cryoapplications (p=0.059) and longer total procedural times (p=0.068) than those with scores <4.
The BAI score showed a trend close to a significant contribution level to the model (β = 0.206, p = 0.059).