Although one isolate (lineage 5) in the mutX deletion group showed a trend toward loss of fitness in both assays—as would eventually be expected in a prolonged mutation accumulation experiment due to the random fixation of mildly deleterious mutations—this change was not significant when analyzed by ANOVA corrected for multiple comparisons.
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In conclusion, serum IGF-1 levels were significantly lower in Pompe disease patients relative to normal control subjects, and serum myostatin also showed a trend for lower levels.
Only the subjects who had the best scores among the sighted group showed a trend to recruit the right fusiform gyrus, indicating that this brain area could potentially play a role in odor recognition in sighted subjects as well.
PETCO 2 showed a trend to increase from baseline to the 2 nd min of the maneuver, however these changes were not significant ( Fig. 2 ).
The observed changes showed a trend similar to those observed from the calendar date basis.
In this experiment, γ-H2AX in both cell groups showed a trend of time-dependent increase.
Sequestered biomass estimates in children with hyperlactataemia or prostration were similar to those in uncomplicated malaria, whereas sequestered biomass was higher in patients with severe anaemia, and showed a trend to higher values in cerebral malaria and fatal cases.
When treated with 1 nM insulin, AS160 KD cells overexpressing RAB10 showed a trend toward increased GLUT4 translocation when compared with control cells.
Additionally, clinical trials showed a trend towards decreased risk for cognitive impairment [18] , [19] , with no effect on coronary events, although these effects must be balanced against raloxifene's known increased lifetime risk of thromboembolic events [20] .
The changes in Col I mRNA and Col X mRNA remained statistically insignificant, but the alginate beads showed a trend towards higher expression of Col X mRNA as compared to the pellets.
In normal subjects, although it showed a trend that LV dyssynchrony parameters acquired from stress scans were smaller than those from resting scans, the differences were not significant.
Triglyceride and glucose levels showed a trend toward suppression in the WLE group, which was considered to result from the mild effect of WLE.
L crispatus and G vaginalis showed a trend of decrease, which however did not reach a log 10 difference.
[ 23 ] showed a trend of longer OS but no significant improvement (HR 0.61, 95% CI: 0.37–1.01) when thalidomide was given as maintenance therapy following ASCT.
Furthermore, sequences related to strain SS2/1 also showed a trend toward an increase after inulin consumption, which could be confirmed by 16S rRNA gene-based qPCR analysis.
Nevertheless, the risk of death showed a trend growing exponentially with the increasing concentration of the Ag suspension.
While time to first on-study relapse was not significantly different between groups (p=0.125), many secondary clinical and radiological endpoints (number of relapses, proportion of relapse free patients, number of new T2 lesions) showed a trend, or were significant (new T2 lesions at month 6) in favoring NTZ.
t-IR levels were similar in allergic and control mice; however, allergy was associated with a significant decrease in the levels of p-IR [95% CI 0.01- 0.31; P < 0.05] in the hippocampus (Figure 6 ) but not in the frontal cortex and hypothalamus, although the data showed a trend similar to that in the hippocampus (data not shown).
Our data also showed a trend for LGE-CMR scar size as a predictor for ICD therapy.
Glutamate concentrations showed a trend similar to the total amino acids; at 144 and 192 hpe, concentrations reached a twofold higher level in non-treated cuttings compared with NPA-treated cuttings (Fig. 8 b).
Compared with the vehicle-treated group,EEP significantly reduced the levels of ET and VEGF,and showed a trend to increase NO and inhibit iNOS.
Subjects 542, 608, 677, and 712 all showed a trend for discordant CD4 downregulation but failed to reach statistical significance (p-value range 0.10–0.17).
Upon EA supplementation, we observed SREBP2 to be statistically significant up-regulated and SCAP to be statistically significant down-regulated, while Insig2 showed a trend towards up-regulation (but was not found to be statistically significant).
Longer sleep duration showed a trend towards correlation with higher LDL while higher PSQI score correlated with higher LDL in model one.
At 6 months, scores showed a trend towards beneficial midterm outcomes for both groups without significant differences between the two groups.