“showed a trend”

In the Phase II TOMORROW trial, treatment with 150 mg of nintedanib twice daily showed a trend to slow the decline in lung function and significantly decrease acute exacerbations in patients with IPF, while showing an acceptable safety profile.

In addition, DNMT1 and DNMT3A showed a trend to reversion of their decreased expression.

Unexpectedly, both mutants showed a trend of changes similar to WT mice for P21 up-regulated and down-regulated gene sets (Figure S7a, c in Additional file 9 ).

Due to safety concerns, there are few clinical trials involving smaller infants, Two recent trials involving 1200 infants with a birth weight of <1000 g showed a trend toward a decrease in the incidence of necrotizing enterocolitis (risk ratio 0.76 [95% CI 0.37 to 1.58]) ( 3 ).

Although CB 1 -KO mice showed a trend towards delayed transit, we did not observe a significant difference between groups (Figure 4 B).

Serotype 1 and 3 showed a trend towards an association with outcome at a significance level of 0.06 for both.

Pancreatic histopathology showed a trend toward a reduction in the low-dose group; at the high dose, there were significant marked reductions in all measures of pancreatic histopathology, approaching control levels ( Figure 5 ).

sobrinus showed a trend to be higher than that of those with S. mutans alone.

These results showed a trend that linear correlations between alpha power and FPV tended to increase from the passive viewing task to the second epoch of the active choice task, with the maximally correlated sites changing from FC1 in the passive viewing to P7 and POz in the active choice tasks.

Patients with anxiety symptoms showed a trend of progression to adverse events, and did not seem to contribute to the association between depressive symptoms and adverse events.

NDGA treatment showed a trend in reducing hepatic TG ( Fig 1B and 1C ), an effect consistent with the restoration of normal plasma TG levels ( Table 2 ).

On the other hand, some of microRNAs (miR-16-5p, miR-100-5p, miR-122-5p, miR-125b-5p, miR-126-3p, miR-143-3p, miR-195-5p, miR-199a-5p, miR-221-3p, miR-342-3p, and miR-574-3p) were only down-regulated or showed a trend to down-regulation just in intrauterine growth restriction pregnancies requiring the delivery before 34 weeks of gestation.

All the above showed a trend that PORT has more obvious advantage in the LN skip group in improving survival.

As a result, she no longer developed DKA during the periods of vomiting and was capable of maintaining her activities of daily living, while repeated cycles of vomiting remitted and glycemic control also showed a trend toward improvement (Fig. 2a, b ).

Participating in the PMP showed a trend towards higher adherence rating by the treating physician (Fig. 2 ).

Consistent with this finding, double labeling and confocal microscopy studies with the oligodendroglial marker p25 and α-syn showed that the total number of oligodendrocytes were not significantly decreased in the striatum, however the levels of α-syn per oligodendroglial cell showed a trend to reduction between animals treated with LV-Control and LV- NR-R80Q-apoB, although this reduction was not statistically significant (Additional file 4 : Figure S4A, B).

While among patients with normal perfusion the QTc interval was unaltered, pregnancies with abnormal uterine perfusion that developed pathological outcomes showed a trend towards shorter QTc.

Many polymeric nanoparticles are designed for efficient delivery, and the CPPs-modified particles showed a trend of increased particle size and a looser complex [ 72 ].

Compared with controls, cases showed a trend towards needing less home visits with no difference in the number of re-training session or technique failure.

Regarding the matched proportions of crescentic glomeruli, ANCA-positive IgAN patients showed a trend of lower eGFR compared with ANCA-negative IgAN patients, but were consistent with AASV patients at baseline [21.2 (10.9, 47.7) mL/min/1.73 m 2 versus 47.0 (8.3, 87.1) mL/min/1.73 m 2 versus 19.5 (9.2, 52.4) mL/min/1.73 m 2 , P = 0.12].

Patients allocated to the intervention group showed a trend toward reduction of HbA1c and BMI at 6 months, which did not reach statistical significance, whereas blood pressure levels did not show any change ( Table 2 ).

By contrast, HO-2 protein levels in both the liver and skeletal muscle showed a trend as being greater in the young adult mice as compared to the older mice ( Fig 4E–4H ).

All groups showed a trend for decreasing values with time after surgery, but no statistical significance was detected ( p =0.132).

Although there were no statistically significant differences between groups, administration of the higher dose of bone marrow mononuclear cells consistently showed a trend toward enhanced neurologic recovery ( Fig. 3f–i ).

Both cell types were equally able to endocytose TR-DX and although the CD14 − CD16 ++ cells showed a trend towards higher internalisation, when the TR MFI was compared to that of the CD14 + cells (Figure 8D ) this difference did not reach statistical significance.