Barely Significant
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“showed a trend”

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In the literature

25 Additionally, a recent report by Bond et al demonstrated that BMI did not differentially influence trough levels of adalimumab and IFX, but the investigators showed a trend towards a lower trough level in adalimumab‐treated patients with a BMI >30 kg/m 2 . 26 Thus, BMI seems to influence the response to adalimumab.
The study showed a trend to reduction in GA progression of 20%, but was not significant. 58 Two phase III trials to investigate the safety and efficacy of monthly or 6-weekly injections of lampalizumab have completed recruiting participants (CHROMA, NCT02247479 and SPECTRI, NCT02247531 ). 59 , 60 Results of the phase III study SPECTRI were recently announced and showed no efficacy.
A retrospective analysis of 81 patients treated for SFTs between 1995 and 2012 in a multicenter study showed positive resection margin was significantly correlated with local recurrence, while tumor size >10 cm, and high mitosis rate were significantly correlated with higher incidence of metastases and showed a trend toward worse overall survival [24] .