Random administration of vitamin D (200,000 IU) or placebo for 240 hospitalized patients with moderate to severe COVID-19 (non-ventilator status) [ 135 ] showed a trend for a therapeutic effect of vitamin D for COVID-19 but this was not significant.
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FRAP activity was expressed by observing the absorbance value, which also showed a trend similar to ABTS + and DPPH activities.
Generally, cognitively worsening groups showed a trend to score worse than cognitively stable groups on a majority of important disease severity markers ( Table 2 and Table S6 ).
Quantitative Analysis The quantitative models showed a trend towards the expected polymorph.
All cancer types showed a trend of overall increased resistance in 3D compared to 2D in vitro tumour cultures.
In a recent study, supplementation of PFA showed a trend towards improving the livability and performance of broilers challenged with Eimeria tenella [ 16 ].
Interestingly, while not significant, the total levels of Akt showed a trend to increase following exposure to unpredictable light cycles.
In silico analysis of the Cancer Genome Atlas (TCGA) data including 412 chemotherapy-naive, invasive, high-grade urothelial tumors [ 3 ] using the Human Protein Atlas platform ( http://www.proteinatlas.org , accessed on 6 March 2021) showed a trend towards longer survival in UCB with high expression of GRHL3; however, it did not reach statistical significance ( Supplementary Figure S6 ) [ 24 ].
The CSB v+t plusSpacer v+t showed a trend of greater TOB concentrations than the Spacer v+t alone throughout the duration of the study, by as much as an 0.77 log difference at h 5 and 6 ( Figure 4 B).
Furthermore, renal transplant recipients with a PyVAN showed a trend towards even higher levels of p70S6k phosphorylation in their CD4 + T and CD19 + B lymphocytes without reaching the predetermined significance level.
Genotoxic Damage An increased DNA fragmentation was observed in the blood of all exposed organisms, particularly prominent in organisms exposed to warming conditions ( Figure 6 A); although not significant, micronuclei frequency also showed a trend of increase in blood of organisms from the warm-treated groups ( Figure 6 B).
The pentose phosphate pathway, an alternative pathway to glycolysis, and the citrate cycle for oxidation of glucose also showed a trend toward enrichment when treated with pep_1E99R5, as did the TGF-β pathway, shown to stimulate the glucose uptake through GLUT1 [ 61 ].
Although only trends have been observed, the results suggest that four of the shortlisted ARE enzymes (CAT, GCLC1, NQO2, SOD2) showed a trend toward decrease in the Treatment group.
Conversely, for patients who used CBZ in combination with phenytoin and phenobarbital or VPA, enzyme-inducing antiepileptic drugs, individuals CYP3A5 wild-type showed a trend of having higher CBZ clearance and lower dose-adjusted CBZ level as compared to individuals carrying the CYP3A5 *3 allele [ 57 , 58 ].
BDNF and NGF expression showed a trend toward statistical significance following increased IBC concentrations in cortical neurons ( Supplementary Materials , Figure S6 ).
The effect of group showed a trend that just failed to reach significance, whereas the time × group interaction was significant.
LIVER DISEASE Individual patient‐level data meta‐analysis of the Liraglutide Effect and Action in Diabetes program suggested that treatment with 1.8 mg of liraglutide significantly reduced alanine aminotransferase in patients with T2DM and abnormal baseline alanine aminotransferase and showed a trend towards improving hepatic steatosis. 9 Studies suggest that in patients with non-alcoholic steatohepatitis, particularly those with diabetes, GLP-1 receptor agonists (including 0.9 and 1.8 mg of liraglutide) may improve liver histology and reduce aminotransferase levels from baseline. 10 Animal stu
Interestingly, KM‐H2‐EBV cells showed a trend on enhancing autophagic flux of LC3‐II but no effect on rescuing DOX‐induced death compared with KM‐H2‐GFP cells (Figure S2 ).
However, the hippocampal CA1 myelination was unaffected after treatment with curcumin, although it showed a trend of decreased coherency (Figure 5F ).
In our study, AST content in both groups was within the normal range; however, it showed a trend of significant decrease after YC addition, which is a positive signal for liver function.
Recent results of a large retrospective analysis of real‐life clinical data from 1,921 patients with ovarian cancer showed a trend for increased rates of germline or somatic BRCA testing, with 25% of patients tested in 2011 to 69% in 2018, largely because of the targeted treatment opportunities with PARP inhibitors [ 22 ].
(range 46.3 D - 94.9 D) at baseline and showed a trend lower (flattening) throughout follow-up.
However, all lines showed a trend toward greater environmental sensitivity for DFC.
In addition, the result of the analysis of the group differences in mean scores of the PROMIS Anger scale showed a trend of higher anger scores in the groups of pure ADHD or ADHD with anxiety/depression than in the depression or tic disorder+ somatic symptoms groups.
Cluster 1 showed a trend toward a decrease in the DEPs, while Cluster 3 trended toward an increase.