“suggestive of significance”

P values falling within the range of 0.00357 to 0.05 were considered suggestive of significance[ 18 ].

All SNP p-values remained suggestive of significance.

A two-sided p-value of less than 0.05 was considered as suggestive of significance.

A q -value of 0.2 was used to identify CpG sites that are suggestive of significance, and a stricter p -value cutoff of 9E-8 was used to call highly significant differentially methylated CpG sites ( Mansell et al., 2019 ).

These 64 VIP genes are known to be expressed in hepatocytes, and owing to the reduced multiple testing burden, we considered a nominal p < 0.05 suggestive of significance.

p values between 2.37 × 10 −4 and 0.05 were considered to be suggestive of significance. 2.4.

A p -value of less than 0.05 was suggestive of significance for this study in view of evaluating the previously 5 significant SNPs.

SNPs that showed an association at P < 1.0 × 10 −5 (suggestive of significance) were selected for independent validation.

Unless specified otherwise, p < 0.025 (0.05/2 databases) was used as a significance level after Bonferroni correction to account for multiple testing, with a 0.025 ≤ p < 0.05 being considered suggestive of significance.

All identified SNPs that reached significance or seemed to be suggestive of significance were visualised using Haploview software [55] .

Meanwhile, associations with p values ≥0.0028 and <0.05 are regarded as suggestive of significance.

The significance threshold is p < .005, considering that many association studies for a single test changed the p value from .05 to .005, and the results with p values between .05 and .005 were considered to be suggestive of significance.

However, since the GWAS was deemed exploratory, we also considered SNPs with p -values below 5 × 10 −5 as suggestive of significance.

Generally, a p value ≤ 0.10 for the Cochran's Q test or an I 2 ≥ 50% was suggestive of significance among-study heterogeneity [ 34 ].

Probes with a Benjamini-Hochberg-adjusted p-value less than 0.05 were considered significant and adjusted p-values less than 0.1 were considered suggestive of significance.

Exploring other associations suggestive of significance reveals several interesting findings, including SNPs in SP110 associated with both lean mass and WC, and WARS2 , associated with HC and WHR.

P-values between 0.05 and 0.0056 were considered suggestive of significance.

Throughout this study, statistically significant differences are denoted when p < 0.005, with p < 0.05 but greater than 0.005 being suggestive of significance.

Importantly, this effect was only seen as suggestive of significance in the LAI adjusted GWAS, suggesting the need for LA adjustment in GWAS of admixed populations such as Caribbean Hispanics.

p values between 0.000350 and 0.05 were considered to be suggestive of significance. 2.4.

Additionally, we considered p-values falling between 6.84E−05 and 0.05 suggestive of significance.

Results with 0.025 ≤ p < 0.05 were considered suggestive of significance.

Three independent clumps were suggestive of significance in the 6-month follow-up analysis ( Table 2 and Fig. 3 ), with no evidence of inflation (lambda = 1.02, Fig. 4 ).

P values between P < 5.38 × 10 −6 and 0.05 were considered suggestive of significance [ 20 , 21 ].

Our results are suggestive of significance of competitive and cooperative interactions in the periodontitis as a novel mechanism of bacterial symbiosis.