Barely Significant
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“trend toward significance”

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In the literature

The trend toward significance across the population was driven by one difference across neuronal types that was significant in a two-way comparison: ROC AUC values for IG complex cells were greater than ROC AUC values for SG simple cells ( P = 0.0012; Fig. 5 A , IG complex cell curve illustrated in dashed cyan).
The abundances of Eubacteriaceae ( P = 0.0823) and Ruminococcaceae ( P = 0.0927) in the Y-TWK10 group, as well as Muribaculaceae ( P = 0.1119) and Eggerthellaceae ( P = 0.1308) in the A-TWK10 group followed a weak increasing trend toward significance when compared to the abundance of these populations in the Y-Control and A-Control mice, respectively ( Supplementary Figure 1B ).
However, we speculate that this is due to the relatively small number of participants in each group resulting from stratification because the trend toward significance for women to show a faster rate of decline remained for all scales, regardless of amyloid positivity or APOE ε4 status.
Gender decoding in early visual areas has been hinted at in previous studies (trend toward significance; Kaul et al ., 2011 ), and anatomical connectivity studies using diffusion tensor imaging support the notion of top-down or recurrent feedback effects via long-range fibre tracts from face areas and the amygdala to early visual cortex (directly or via the occipital face area; Gschwind et al ., 2012 ).