Longitudinal measures of peripheral optical quality in young children.

Ophthalmic Physiol Opt · 2025 · PMC11823306 · PMID 39865325

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

approaching significancep = 0.06so close (0.05 < p ≤ 0.1)

No significant differences were noted in AXL between children at LR and HR for myopia at any specific visit ( p ≥ 0.06 for all), approaching significance at V7 ( F = 3.64, p = 0.06).

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showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

In terms of changes over time, generalised linear models with age as a covariate showed a trend towards smaller (worse) HO-SR with time (area for the entire retina: F = 2.01, p = 0.06; Figure 4a ).

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a clear trendno p-value reported

40 Although this is the case for metrics that include all HOAs, such as the HO-Strehl Ratio (HO-SR) or HO-Root-Mean-Square (HO-RMS), there is a clear trend for individuals with myopia to have less positive or more negative primary spherical aberration [SA, Zernike coefficient C(4,0)]. 24,26,29,34,36,41–43 It has been suggested that this association of SA and myopia may be simply a consequence of the longer axial length in myopes, but this does not see

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did not reach statistical significanceno p-value reported

When the analyses were repeated with subjects categorised into LR and HR for myopia, the results did not reach statistical significance.

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