Utilizing non-invasive biomarkers for early and accurate differentiation of uncomplicated and complicated acute appendicitis: a retrospective cohort analysis.

Sci Rep · 2025 · PMC11842546 · PMID 39979418

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

approached significancep = 0.06so close (0.05 < p ≤ 0.1)

In multivariate analysis, appendix diameter remained significant ( p = 0.01), and male sex approached significance ( p = 0.06).

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showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

did not reach statistical significanceno p-value reported

In the multivariate logistic regression analysis, male gender showed a trend toward being a risk factor for complicated appendicitis ( p = 0.06), but this did not reach statistical significance.

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near-significantno p-value reported

Male sex approached significance, indicating that it was a near-significant independent predictor of complicated appendicitis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.