Barely Significant
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Mediterranean Diet Patterns Are Positively Associated with Maximal Fat Oxidation and VO<sub>2</sub>max in Young Adults: The Mediating Role of Leptin.

Nutrients · 2025 · PMC12157293 · PMID 40507170

Europe PMCDOI
4
hedged sentences
0.1000
closest p · 2.0× alpha
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boldest claim

The sentences

showed a trendp < 0.1so close (0.05 < p ≤ 0.1)
After adjusting for age or both sex and age, associations with MFO and VO 2 max persisted, while those with the BMI and leptin were attenuated and showed a trend ( p < 0.1).

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did not reach statistical significanceno p-value reported
A similar trend was observed for VO 2 max in the unadjusted model, although this association did not reach statistical significance after adjustment. 3.3.

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approached significanceno p-value reported
For MFO relative to body mass, the indirect effect approached significance (β = 0.080, 95% CI [−0.011, 0.195]; Figure 1 C), with a significant direct association and a trend observed in the leptin-to-MFO path ( p = 0.0876), suggesting possible partial mediation.

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a negative trendno p-value reported
In line with this evidence, our study showed a negative trend in the association between leptin levels and VO 2 max and also found that leptin significantly mediated the relationship between MedDiet adherence and VO 2 max.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.