Replication of the GWAS-Identified GALNT13 rs10196189 Polymorphism in Relation to Speed-Power Elite Active Athlete Status and Multidimensional Phenotypic Differences in Chinese Han Males: A Pilot Study.

However, medial gastrocnemius thickness showed a nominally significant association with the G_carrier genotype (β = 0.371, p = 0.0112; FDR-corrected p = 0.1683), suggesting a potential link between this genotype and muscle architecture in specific regions ( Table 7 ).

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Differences in Genotype and Allele Frequencies Between Athlete and Control Groups The distribution of GALNT13 rs10196189 genotypes showed a marginal statistical difference between the athlete and control groups (χ 2 = 4.85, degrees of freedom = 2, p = 0.088), and the Fisher’s exact test also approached significance ( p = 0.069).

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AA + AG) still did not reach statistical significance (OR = 2.68, 95% CI: 0.10–68.93, p = 0.490).

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Additionally, some phenotypes, such as IMTP absolute peak force (β = 537.93, p = 0.066) and rectus femoris thickness (β = 0.25, p = 0.084), demonstrated near-significant trends that may carry biological relevance.

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