Expression Patterns and Clinical Relevance of HSP70 and Metallothionein in Triple-Negative and Luminal A Breast Cancer: A Croatian Cohort Study.

Cells · 2026 · PMC12938892 · PMID 41744793

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.5080

boldest claim

The sentences

showed a trendp = 0.053so close (0.05 < p ≤ 0.1)

nearly statistically significantno p-value reported

The Ki-67 proliferative index showed a trend toward a decreased risk for tumors with more than 20% positive cells (HR 0.336; 95% CI 0.111–1.014; p = 0.053), which is nearly statistically significant and may indicate a potential influence of cell proliferation on DFS.

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did not reach statistical significancep = 0.508not close (p > 0.1)

Although the Kaplan–Meier curves indicated a less favorable survival trend in the TNBC group, the difference did not reach statistical significance (log-rank test: χ 2 = −0.66, p = 0.508).

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a clear trendno p-value reported

The log-rank test confirmed that the difference in DFS between the groups was not statistically significant (χ 2 = 1.87; p = 0.062), although a clear trend toward shorter DFS in TNBC patients was observed.

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