showed a trendP < .3
Variables that showed a trend for association with survival ( P < .3) were selected for inclusion in the final multivariate Cox proportional hazards model [ 22 ]. 3.
Variables that showed a trend for association with survival ( P < .3) were selected for inclusion in the final multivariate Cox proportional hazards model [ 22 ]. 3.
An elevated preoperative lymphocyte count and INR exhibited a significant univariate relationship with decreased overall survival in patients undergoing resections of CRLM in our series; however, these parameters did not prove to be independent predictors of prognosis as they failed to reach significance on multivariate analysis. 4.3.
However, both nodal involvement and bilobar disease demonstrated a clear trend towards less favourable overall survival.
Of the haematological parameters assessed only preoperative platelet count showed a strong trend of association with disease free survival; however this failed to reach statistical significance ( P = .076).