highly significantp=2.25e-14
Results: Logistic regression analysis showed a highly significant effect of the haplotype ranks in the outcome of a search in BMDW (p=2.25e-14).
Results: Logistic regression analysis showed a highly significant effect of the haplotype ranks in the outcome of a search in BMDW (p=2.25e-14).
The FACT-BMT Total score approached significance in favor of SoC + ECP (−1.7842, P= 0.057).
Regarding the best time to transplant in the disease course, there was a near significant trend for improved outcome in the MAC setting when recipients underwent allo-HSCT within the first year of diagnosis compared to those transplanted later (p=0.08).
Incidence of chronic GVHD did not reach statistical significance between MUD 75.5% (95% CI: 63.9-83.8%) and sibling donors 65.5% (95% CI: 54.1-74.7%), (p=0.13).
In our series, a high variability in antibodies titers at baseline was shown; however, most patients showing a protective titre against the tested agents showed a trend to maintain it.
On multivariate analysis, age was an independent predictor of NRM (HR 1.16; p = 0.0099), while KPS of 70-80% (HR 2.16; p = 0.069) and MA conditioning (HR 2.95; p = 0.081) showed a strong trend toward greater NRM.