Furthermore, also the TNM-categories showed a highly significant correlation with the 5-year OS: a high pT category and positive lymph node (pN) status predicted a worse 5-year OS with high significance ( p < 0.001).
Excerpts
In contrast, we examined a highly significant difference between SPT and OPT, comparing AVDG to CG ( p < 0.001) and AVDG to ADG ( p < 0.001), but not for ADG to CG ( p = 0.348).
When stratifying patients into two groups at six points or higher, a highly significant difference in the occurrence of postoperative seizures between the two groups was noted (Pearson Chi 2 : p < 0.001).
Case 8 showed highly significant changes ( p < 0.001) in size-related parameters (nuclear area, equivalent diameter, and circumference) and density measures, except for the area and diameter between the second and third recurrence ( Figure 7 a).
As shown in Figure 2 a, adding ifenprodil resulted in a highly significant decrease in 53BP1 foci (1.6 ± 0.2, p < 0.001) when compared to the Glu treatment alone, whereas adding NBQX led to a significant lower decrease of the number of foci compared to ifenprodil (1.95 ± 0.16, p = 0.026).
Overall, the effect of the intervention remained highly significant after accounting for clustering by site (χ 2 = 55.16, p < 0.001). 4.
They found a highly significant difference in both HPV-associated OPSCC DSS (log-rank p < 0.001) and PFS (log-rank p < 0.001), with higher TIL levels linked to longer survival.
For the investigated time frame, a highly significant decrease ( p = 0.001) in survival rate of CAP treated eggs was observed.
The overall pooled effect was highly significant (Z = 8.77, p < 0.001).
DEGs Evaluation First, we identified lists of highly significant DEGs (FDR-adjusted p -value < 0.001) for GII vs.
The log-rank test indicates a highly significant result, with p < 0.001.
Kaplan Meier analysis considering tumor size exceeding 800 mm 3 as an endpoint showed a highly significant difference between curves ( p = 0.001) ( Figure 6 A,B).
Second, according to Figure 10 , a strong and highly significant positive correlation was identified between the number of lymph nodes examined and the number of lymph nodes invaded (rho = 0.65, p < 0.001; Figure 5 ).
Statistical significance was defined as significant (* p -value ≤ 0.05), very significant (** p -value ≤ 0.01) and highly significant (*** p -value ≤ 0.001). 5.
Compared to the corresponding normal tissue, a highly significant expression ( p < 0.001) was found in eighteen tumor tissues, including bladder urothelial carcinomas (BLCA), invasive breast carcinoma (BC), cholangiocarcinomas (CHOL), colon adenocarcinoma (COAD), esophageal carcinomas (ESCA), glioblastoma multiforme (GBM), squamous cell carcinoma (SCC) of the hea
The statistical comparison indicates a highly significant difference in expression levels between diagnostic and relapse cases ( p < 0.001), suggesting that WT1 expression dynamically reflects disease burden and treatment response.
Further, the Kaplan–Meier curves of the metastasis-free survival showed a highly significant worse clinical course for the high-risk group (log-rank test: p < 0.001), and we demonstrated superiority over other established risk factors.
Therefore, with unequal variance, there is a statistically highly significant difference, which can be explained by the composition of the collective ( p < 0.001).
The observed PDT effect after illumination was curcumin dose-dependent and highly significant ( p < 0.001).
Of note, all ICCs were highly significant ( p < 0.001), with correlations ranging from moderate (8’ walk, 0.47), to strong (8’ get-up-and-go, 0.74), to very strong (30 s chair stand, 0.80; sit-and-reach, 0.86; 2 min step test, 0.87; back scratch, 0.90; weight, 0.93; and waist circumference, 0.98).
Results: Multivariable GEE analysis demonstrated that the Systemic Immune-Inflammation Index (SII) was a highly significant independent risk factor (OR for a 500-unit increase = 1.490, 95% CI: 1.234–1.798, p < 0.001).
Statistical significance was defined as significant (* p value ≤ 0.05), very significant (** p value ≤ 0.01), and highly significant (*** p value ≤ 0.001). 5.
In addition, a significant trend of increasing risk of breast cancer was observed when p16 INK4a mRNA expression increased ( p < 0.001).
A more pronounced and highly significant increase was seen in somatic testing, which rose from 23.7% (193/814) to 44.2% (234/529) ( p < 0.001).
The narrow confidence interval and highly significant p -value ( p < 0.001) further support the reliability and clinical relevance of this finding.