Excerpts

However, there was a slight trend towards larger immature moDCs.

In multivariate analysis, there was only a slight trend toward less common weak responses to immunization with rHBsAg in the late vaccination group.

Patients with severe cGVHD showed a trend toward lower median Ab titers, although they required a higher rate of booster vaccine doses.

Instead, there was a clear trend that ssON treatment reduced the cell death by up to 25% in the cell cultures exposed to the highest MOI 1 ( Figure 1C ).

We believe that the identification of such high BCR sequence convergence between geographically distinct and independent datasets could be highly significant and validates the disease association of the clonotypes, as well as the overall approach.

While LPS triggered a reduction in Ifng -mRNA, a slight but highly significant increase in IFNγ was detected ( Figure 5D ).

However, when assessing TNF-α and Hb genotypes when compared with and without malaria there was no tight association, but there was an increasing trend in TNF-α levels in malaria positive groups ( Figure 1 ).

The genotype combination 131HH/176FF/NA1NA1 indeed showed a trend towards a higher risk of infection in a low-risk environment ( Table 8 ).

In addition, Fas protein showed a trend of increase in the adipose tissue of obese subjects compared with lean subjects, and was more highly expressed in adipose tissue of T2DM obese subjects compared with non-T2DM obese subjects ( 33 ).

The cumulative impact of these therapies and stressors is likely to be significant.

Despite an evident trend in the increased WAM of AACT across four-time points observed in all patients, we observed significant differences in glycoproteoform profiles between the different patients, which indicated that the T1 baseline glycoproteoform profile for each patient is already quite different.

Overall, based on the statistical analyses of the survival curves ( Figure 2 ) and of the scatter plots for bacteremia ( Figure 3A ), highly significant differences were found between the groups of mice treated with both E-CRP-1 and clarithromycin and the groups of mice treated with either agent alone.

This region may be significant for intracellular processing and trafficking during protein synthesis ( 59 ).

CD4 + T cells in the ear tissue showed an increasing trend, though the difference was not significant.

However, one study found worse treatment outcomes in patients who took metformin plus ICIs with a nonsignificant trend ( 32 ).

A P value < 0.05 (*) suggests statistical significance; P < 0.01 (**) suggests very significant differences; P < 0.001 (***) suggests extremely significant differences.

There was a clear trend that the difference of HLA-DR expression on day 6 compared to the first 4 days was higher in patients surviving sepsis.

Real-life case series had further confirmed this significant impact on oral ulcers and demonstrated a positive trend on genital ulcers in smaller samples ( 14 – 16 ).

In a post hoc analysis by weight group, patients over 100 kg treated with the 90 mg dose showed a trend to higher American College of Rheumatology (ACR) and Psoriasis Area Severity Index (PASI) response rates than those treated with the 45-mg dose ( 106 ).

Other factors, notably mother’s age and household density with positive trends and cesarean delivery with a negative trend, showed association with numerous antibodies, but also did not remain significant after adjusting for the false discovery rate.

These results imply that these TRs may regulate the infiltration of leukocytes and their activation might be significant in controlling ICH.

C3 and properdin showed a positive increase on exposure to global radiation, while FH showed a decreasing trend.

A 2006 report assessed periodontitis in patients diagnosed with IBD using a case-control study design and again showed a trend toward lower severity, but higher periodontal disease prevalence, in IBD patients ( 87 ).

Despite the small number of patients (n=23), highly significant and consistent changes were observed, with SAA (11.6 kDa) showing the biggest decrease in expression upon the treatment.

Here, we observed significant positive correlations for CD8 MAIT among T1D subjects with a positive trend in among controls ( Figure 3C ).