Barely Significant

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highly significantqualifiedgold
3.3 Bacterial and fungal community structures The results of PCoA indicate that the differences in bacterial (r = 0.9974, p = 0.001) and fungal (r = 0.9974, p = 0.001) communities among different treatments were both highly significant ( Figure 2 ).
In this study, we observed a decreasing trend in the abundance of Firmicutes and Bacteroidetes after exercise fatigue compared to pre-exercise levels, suggesting that strenuous exercise leads to dysbiosis in the gut microbiota, affecting the intestinal barrier and function, aggravating endogenous inflammation, and leading to weakening of host intestinal digestion and absorption, which in turn aggravates the accumulation of fatigue.
In this study, the DSS-induced intestinal inflammation model exhibited typical SCFA metabolic disorders: the content of butyric acid was abnormally elevated (which may be related to abnormal fermentation caused by intestinal microbiota imbalance), the content of isovaleric acid was significantly reduced, and valeric acid showed a decreasing trend.
producta 1009924 fermentation broth, the contents of butyric acid, valeric acid, and isovaleric acid in the intestines of model zebrafish all showed a trend of normalization—not only reversed the decrease in isovaleric acid and valeric acid, but also potentially restored the physiological function of butyric acid by optimizing its abnormally high expression.