Barely Significant

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However, the results of the included studies are insufficient to indicate a favorable trend from the effects of BFR in the long term and follow-up; therefore, future studies are required to evaluate these periods in order to demonstrate whether its effects are maintained or improved with respect to high-load or aerobic exercises.
If we consider the change in physical activity practiced before COVID-19 and during lockdown, a significant increasing trend (within-group comparison) of the frequencies was observed for younger age groups ( Z = 2.73; p < 0.01), while a decreasing trend was shown by subjects in the three older age groups.
In addition, the risk of alcohol drinking was lower in patients with a longer period of abstinence before inclusion in the univariate analysis, as craving and other negative effects tended to decline over time after patients initiated abstinence [ 40 ], but this relationship became marginally non-significant in the multivariate model.