This approach allows for the observation of a clear trend whereby increasing concentrations of the drug are associated with a progressive decrease in the number of dividing nuclei, indicating a concentration-dependent effect on cellular proliferation.
LNCaP cells also showed an increasing trend in proton leak, which may be linked to damage to the inner mitochondrial membrane [ 51 ], and non-mitochondrial respiration typically increases with cellular stressors such as ROS.
Examining the variation in the band gap with the ionic radius of the M-site cation reveals a clear trend: as the ionic radius increases along the series Li < Na < K < Rb, the band gap systematically decreases.
By comparison, the TC RNA amplification method using the same amount of mouse whole brain input RNA 1 ng ( Figure 3E ), 10 ng ( Figure 3F ), 25 ng ( Figure 3G ), and 50 ng ( Figure 3H ) displays a highly significant increase in hybridization signal intensity.
Complementary Strand Interactions The structural competitive mechanism between the G-quadruplex and the Watson-Crick duplex is extremely significant due to its biological implications.
The metathesis activity showed a decreasing trend with catalyst 1 according to the solvent/anion order BF 4 − > NTf 2 − ~ PF 6 − .
This might be significant in the context of ischemia, in which intracellular Ca 2+ overload has been implicated as a primary mechanism of neuronal injury [ 35 – 37 ].
E40K was also nominally significant for triglycerides in the Mexican American populations even with a very small count of nine heterozygotes carrying the K variant (haplotype H96).
The results of this experiment comparing the proliferation index of tumors treatment with low-and high-dose Celecoxib showed a trend toward a dose-dependent proliferation inhibition response.
The worst predictions are for 5 and 6 , and it may be significant that conformations of these two less sterically-hindered substrates are predicted to be twisted but not perpendicular; then the solvent may have a greater influence on the conformation and hence on changes in conjugation energy during ionization.
Although the LOH frequency at each locus showed an increasing trend with increasing disease severity, the difference was not statistically significant.
The results showed the nonlinear regression of the SVR3 model ( R 2 = 0.947) was highly significant because its F value (21.017) was greater than F 0.01 (7, 10) value, and the nonlinear regression of the SVR4 model ( R 2 = 0.947) was significant because its F value (7.310) was greater than F 0.05 (11, 6) value.
Additionally, the effects of exogenously applied ABA and Flu on the above mentioned parameters were highly significant.
An increasing trend in the glucose concentration through time was observed in all animal groups, which could probably be attributed to the aging of the mice.
Current generation showed a decreasing trend with an increase in R ext , which is consistent with the literature, and indicated typical fuel cell behavior.
The F -value, 64.22, implied that the model was highly significant.
Although there was a highly significant 25% proportional reduction in the first event rate for stroke, there was no significant reduction in the recurrence of stroke in this study.
An F test suggested that the model had a very high model F -value ( F = 83.52), indicating that this model was highly significant.
Based on the roles CL performs in the mitochondria, the functional consequences of accruing 22:6 into the structure of CL are likely to be significant.
Significantly higher numbers of Annexin V-positive/PI-negative (apoptotic) cells were evident in the ICM of treated blastocysts compared to controls, but no such difference was apparent in the trophectoderm (TE) ( Figure 2B ).
Although the steps of transmigration (rolling, adhesion and transmigration/diapedesis) may show some similarities, due to different physiological, molecular and mechanical characteristics of immune and metastatic cells, there may be significant differences [ 50 ]. 3.1.
p < 0.05 was considered statistically significant and p = 0.05 to 0.10 marginally significant. 5.
A p value of 0.05 was considered significant, and a p value of 0.01 was considered highly significant. 4.
Differences between samples were considered statistically significant for p < 0.05 and highly significant for p < 0.001. 4.
These scaffolds can easily be tuned by varying their compositions to obtain the desired level of sericin release, which may be significant in terms of wound healing and tissue engineering [ 24 ].