Barely Significant

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extremely significantp < 0.00010.0× alphaqualified
For overall patients, we found a direct, weak, but extremely significant association between transient elastography and APRI ( r = 0.22, p < 0.0001) ( Figure 2 A) and between transient elastography and FIB-4 ( r = 0.21, p < 0.0001) ( Figure 2 B.
highly significantp < 0.00010.0× alphaqualifiedgold
Patients with migraines (MIG-group in Table 1 ) were all females, had the youngest age (53.0 years in the mean), had the longest time to therapy (24 years in the mean!), were exclusively treated with onabotulinumtoxin (onaBoNT/A), and reported the best highly significant ( p < 0.0001) relative mean improvement (100 − (RS-%)) of more than 65% and suspected only a mild non-significant ( p > 0.05) further worsening ((SS-%) − 100 = SWORS-%) of less than 10% in the mean beyond the level of severity at onset of BoNT therapy.
highly significantp < 0.00010.0× alphaqualifiedgold
A highly significant trend emerges from the data (Cochran–Armitage Trend Test = −4.72, p < 0.0001): as the absolute value of the Tmax/Dmax ratio increases, the physiological outcome decreases, from 52.4% in the first quartile, 33.3% in the second quartile, 14.3% in the third quartile to 0.0% in the last quartile, respectively.
highly significantp < 0.00010.0× alphaqualifiedgold
Conversely, when false negatives were regarded as more critical, the standardized examination again yielded a substantially higher average kappa (0.59, SE = 0.023) relative to the non-standardized method (0.45, SE = 0.027), with this difference being highly significant ( p < 0.0001) and a 95% confidence interval ranging from 0.07 to 0.21.