7WD10 cells exposed to different concentrations of 2-CDA revealed highly significant reductions at 0.1 μM (39%, p<0.001), at 0.5 μM (30%, p<0.001), 1.0 μM (24%, p<0.001), 5.0 μM (19%, p<0.001) and 10.0 μM (29%, p<0.001) compared to untreated control cells ( Figure 7A & B ).
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There was also a directionally similar borderline significant difference between inverted faces and angry faces ( Mdn = 261.68 ms), Z = 2.50, p = .001, r = .30.
The Q-statistic for subgroups differences was highly significant for SBP and DBP in both genders (p<0.001 for all).
The 4 fold higher ratio in the rod TSSs was highly significant (p = 0.0011).
Correlation analysis between fluorescence intensity and tumor volume over the entire duration of the experiment showed a highly significant correlation (Pearson = 0.9469, p-value = 0.0011), thus establishing the ability to reliably measure tumor load and growth using cells expressing far-red fluorescence proteins.
A significant trend over time was observed in both CD107a+,IFN-γ+ (p = 0.0011) and CD107a single positive (p = 0.0247) CD8+ T cells, with an increase at M2 and M3 and a reduction in the following months.
Subregional analyses revealed that this increase was highly significant in the caudal DG (71%; p = 0.0011), but non-significant in the rostral DG (p = 0.29) ( Fig. 2A ).
A highly significant correlation (rho = 0.775; P <0.0011, Spearman's rank correlation) between array and qPCR results was found, indicating that both methodological approaches yielded similar results and identified the genes that were either down- or up- regulated with accuracy ( Figure S2 ).
We also found a nominally significant association between an exonic variant in ULK1 and triglycerides (p-value = 0.0012).
Given that only 13.3% (3004/22500) of the probes analyzed were overexpressed in those experiments, this enrichment is highly significant (p = 0.0012; Chi square test with Yates correction, 1 degree of freedom).
Based upon the frequency of these alleles in the SDP (11/18 alleles for the upstream marker and 0/18 alleles for the downstream marker; Table S3 ), this difference is highly significant ( p = 0.0012 for the upstream markers, p <0.0001 for the downstream marker, Fisher’s exact test).
A one-sided t-test on the personal axis is borderline significant ( μ : 57.35, σ : 8.53, CI : [53.94, 60.77], t (23) = 4.22, p = 1.29 × 10 −3 , d = 0.86).
Changes were highly significant ( P = 0.0013 for the acute response, P = 0.0060 for the long-term response).
Indeed, we found that potentiation of EPSP amplitudes increased by 166.0±8.9% for rats housed in conventional cages (n = 13; t = 45−50 min after TBP, p = 0.0001) and by 227.0±14.4% for rats raised in MarlauTM cages (n = 12; t = 45−50 min after TBP, p = 0.0001), the difference in LTP amplitude between the two groups of rats being highly significant (p = 0.0013).
Comparing total survival in the nlpD -vaccinated mice to EV76-vaccinated mice by Chi-square analysis revealed highly significant difference (P = 0.0013).
The difference between cells co-injected with collagen and SISgel was highly significant (p = 0.0013), but the difference between cells co-injected with collagen and Matrigel was not (p>0.05).
Additional data from our laboratory (not shown) found highly significant (p = 0.0014) overlap between some of these miR targets and proteins associated with sensitivity to cisplatinum.
the association remained highly significant when crust type was specified as a random effect in the analysis (P = 0.0014).
In addition to these decreases, CRP levels showed a highly significant increase (P = 0.0014**), suggesting an inflammatory response related to cancer.
On the other hand, the difference between the asymLSF and symLSF conditions was highly significant ( t (6) = 5.603, p = .0014 for the female-face condition, and the difference between them for the male-face condition was obviously significant but beyond the measurable range.
The index SNPs met the Bonferroni corrected significance level for QT duration, but fell just short of significance for PR duration ( P = 1.44E-03).
This variable was highly significant in the model (p = 0.0015).
Wax is also the primary source of the much lower bee residues of the other major hive miticide, coumaphos, as indicated by the highly significant correlation of wax and bee contents (wax coumaphos = 54.2 • bee coumaphos +1383 ppb; r 2 = 0.484, p = 0.0015, n = 58) compared to the non-significant correlation of pollen and bee residues (r 2 = 0.00585, p = 0.630, n = 42).
A similar, but non-significant trend was evident among the HUB1 line individuals ( Table 3 ), together yielding a highly significant Fisher's combined probability of P = 0.0016 [ Χ 2 = -2*(ln(0.011)+ln(0.141)) = 12.94 with DF = 2].
However, because this term is associated with a large numbers of transcripts (1187) the enrichment is highly significant (p = 0.0016 at FDR≤10 −6 ), consistent with the role of this metabolic compartment in light-grown plants.