Excerpts

Only one variant (rs999741 in the HTR4 region, MAF 26%) had a nominally significant P-value (P = 2x10 -3 ) and had consistent direction of effect in stage 1 and stage 2 ( S4 Table ).

Comparison of the frequency of amplification among these three groups is highly significant with p = 0.0020 and 0.0011, comparing the first group with each of the second two groups (Fisher's exact test).

Overall, the difference between employed and unemployed candidates on the interview measure was highly significant d = .274(.094, .459), Z = 2.912, p = .002, one-tailed.

The age and sex adjusted interaction between DM and CVD in predicting mortality was highly significant (p = 0.002) and persisted after accounting for comorbidities and treatment factors (p = 0.006).

For the species analysis along with the explanatory variables the unrestricted Monte Carlo permutation tests (499 permutations) of the significance of the canonical axes indicate axis 1 as statistically highly significant (p = 0.002).

Furthermore, the plasma triglycerides-to-HDL ratio, a known marker for metabolic syndrome and highly atherogenic dyslipidemia,[ 18 ] showed a highly significant correlation with mFD (r = 0.480, p = 0.002).

In the 53 observations where the IgG Index is ≤ 1.14, there is a highly significant positive correlation between number of OCBs and the IgG Index ( r = 0.39, slope = 11.45, se = 3.74, p = 0.002); however, in the 16 observations where the IgG Index is greater than 1.14 but less than 1.9, the slope decreases, but not significantly so ( r = -0.14, slope = -6.09, se = 11.68, p = 0.68) ( Fig 2C ).

However, at the end of the intervention, a highly significant difference could be noted between the groups, with a higher score in the active treatment group (t = 3.11; P = 0.002).

The effect of DNMT3A genotype on birth weight and DNMT3B on length of gestation were the least significant before the exclusion and just below significance following the reduction in numbers; though the stronger DNMT3B effect on risk of prematurity remained highly significant (p = 0.002) after exclusion of the non-Caucasian pregnancies.

This variable explains 5.2% of total OTU variation and is highly significant (pseudo-F = 11.0, P = 0.002).

During the stimulus-driven attentional paradigm, the mean correlation values in the beta range (16–24 Hz) obtained for all electrode pairs (in areas 17 and 18) during the correct visual trials (0.63 ± 0.06; Fig 5A , gray boxes) were smaller than those calculated during the (correctly performed) auditory task (0.71 ± 0.05; Fig 5A , black boxes), and this difference was highly significant (n = 20 electrode pairs, P = 0.002, paired t-test; see also S5 Fig ).

Comparing JNDs of single subject data before and after training shows that this categorical effect is highly significant (Wilcoxon signed rank p = .002, T = 0, r = −.845, effect size W = .89).

Also over parieto-occipital sites, an interaction by task by hemisphere approaching significance specified this P3 difference in users to be present over left sites for implicit, t (62) = 3.289, p = .002, d = .70, and explicit, t (67) = 3.251, p = .002, d = .72, but not empathic processing, t (68) = 2.046, p = .045, d = .51; while right sites showed no group differences (implicit: t (68) = 1.622, p = .109, d = .40, explicit: t (68) = 2.283, p = .026, d = -.40, empathic: t (68) = 2.192, p = .032, d = .55).

RDA ordination (growth response) Results of Monte Carlo permutation tests showed highly significant effects ( p = 0.002 with 499 permutations) of the influence factors on the growth responses of the T . distichum trees.

When compared to controls, patients with DIE had the lowest birth weight with a highly significant difference (3,103g ± 620, p = 0.002).

The results of that analysis, shown in Figure 3 , confirm that degree of perturbation was more difficult to distinguish for some PL animations compared to others, but the pattern of results was the same for healthy controls and patients, with the correlation between groups being highly significant (r = 0.85, p = 0.002).

90 minutes of exposure to UV light resulted in a highly significant (p<0.002, n = 20) increase of gross O 2 production in the Ageladine A treatments vs. the controls (2.34 ± 0.38 and 0.92 ± 0.32% h -1 , respectively; Fig 1b ).

There was highly significant genotypic differentiation (Fisher's exact test = P<0.002, df = 14) within populations for all loci except Dicten18 and Dicten27 (Fisher's exact test = P>0.1, df = 14).

ip transmissions show only a trend towards significance (P = 0.002).

The regression retained only skin yellowness as a predictor of attractiveness, and the effect of skin yellowness was positive and highly significant (F(1,71) = 10.806, Beta = .366, t = 3.287, p<.002).

The increase in ELISPOT response at one week was highly significant for Ag85A peptides (p = 0.002), Ag85A protein (p = 0.004), and PPD-T (p<0.001).

The populations were separated into two major groups along the second axis of the PCA, which was highly significant (original dataset, p = 0.002 and corrected data set, p = 0.001).

The significant interaction reflects that there was no significant difference between the reporting of the two modified motif types in the unfamiliar condition (p = 0.452, average response latencies for discriminating gap and noise motifs from the from the background of complete motifs were 1002 and 955 ms, respectively), whereas there was a highly significant difference in the response latencies for reporting the two modified motif types in the familiar condition (p = 0.002, average response latencies for discriminating gap and noise motifs from the from the background of complete motifs were 1219 and 1478 ms, respectively).

Comparing CYP26B1 negative and weakly positive tumours with CYP26B1 moderate and strong expressing tumours showed that there was a highly significant association with survival (HR = 1.465, 95%CI = 1.151–1.865, χ 2 = 9.832, p = 0.002).

Although the number of cells did not decrease to the levels found in control non-sensitized animals, the decrease was dose proportional and highly significant (p < 0.002) when compared to OVA-sensitized mice which did not receive ASM-024.