At the protein level, treatment with pLECs-CM led to a highly significant increase in IL-6 concentration in the cell culture supernatants of both the LFC and AN-LFC (p < 0.0001).
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mansoni cathepsin B1 (SmCB1), or a cathepsin L from a related parasite Fasciola hepatica (FhCL1), elicits highly significant ( P <0.0001) protection (up to 73%) against an experimental challenge worm infection.
However, in the animals exposed at 115 dB SPL, the increases in ASR amplitude were highly significant at all stimulus levels from 105–120 dB SPL ( Fig. 4D ) (F 3,80 = 38.57, P<0.0001) and followed an initial period when startle responses were decreased below control levels ( Fig. 4C ).
The results are highly significant (p<0.0001, Table 2 ), and indicate that MYC IHC can identify a set of tumors with transcriptional profiles resembling those previously categorized as mBL.
In our study, we observed a highly significant increase ( Table 2 : p ≤ 0.0001; FC = +8.187) in hypoxanthine excretion in all 20 cases studies, which peaked at one hour after alcohol consumption in 18 of the cases, and at 2 hours in the other two cases ( Fig 4E ).
By two-tailed t-test, all markers exhibited highly significant (P<0.0001) decrements in immunoreactivity in the AD twin compared to the ND twin ( Figure 2b ).
Two-way ANOVA analyses proved that the cortisol treatments affect male and female cell responses differently; the interaction was considered extremely significant (interaction p value < 0.0001; F = 392.7; DFn = 2).
All pair wise distances were highly significant ( p < 0.0001).
Cells expressing the control CYC1 3′UTR reporter showed little difference in the population mean fluorescence intensity (MFI) when Ssd1 was absent (0.87-fold change in expression in ssd1Δ compared to SSD1 ), while cells containing the test CTS1 3′UTR construct exhibited a nearly three-fold, highly significant increase (p<0.0001) in MFI in ssd1Δ cells compared to SSD1 cells ( Figure S1A ).
Highly significant differences in the transmission rate (% C Las-positive inoculated leaves) were found between various lines ( Table 6 , P = 0.0001).
This highly significant difference (p<0.0001) indicates that EdU-negative mitotic cells (pH3 positive) had been in G2- or M-phase for at least 24 hours prior to fixation.
Comparison of the hourly mean values of P1 with those of P2 yields a highly significant correlation coefficient (p < 0.0001, n = 24).
A Wilcoxon test showed highly significant differences between the groups (χ 2 = 64.7, DF = 2, p< 0.0001).
There was a highly significant linear correlation for mice and rabbits (data not shown) (r = 0.847, P<0.0001 & r = 0.809, P = 0.0008, respectively, Pearson), whereas the linear dependency for rats was somewhat lower (data not shown) (r = 0.476, P = 0.01, Pearson).
Unpaired t-tests comparing the seronegative and seropositive populations yielded highly significant p-values (p<0.0001) for both the Immunetics® C6 Lyme ELISATM ( Fig 2A ) and the MicroB-plex Anti-C6/Anti-pepC10 Immunoassay ( Fig 2B ).
Additionally, non-parametric one-way ANOVA analysis for comparing methylation levels of one loci in different tissues was highly significant for all loci (CpG-1 and CpG-2 for both male and female subpopulations, Krustal-Wallis test, p<0.0001) A relatively greater level of methylation was observed in most tissues at IAP-LTR, Line-1 and Myc .
A difference from global connectivity is that in this case the difference between healthy and control subjects is clearly significant (p-value < 0.0001).
Critically, simple main effects confirmed that differences in atypicality between fluency and mastery portraits were highly significant for both phases, t1 ( M diff = 3.00), F (1, 11) = 214.08, p < .0001, p 2 = .951 and t2 ( M diff = 2.20), F (1, 11) = 36.46, p < .0001, p 2 = .768.
Hence, the association of clade (C) with infections in horses is highly significant (p<0.0001; chi 2 test).
Relative abundance of Myoviridae had a highly significant negative correlation with latitude (R = - 0.671, p < 0.0001) and a positive correlation with longitude (R = 0.484, p < 0.0001).
The overall Fst estimate across all loci was 0.373 and was highly significant (P<0.0001).
Protein signature analysis The correlation between the logarithm of the neuroscience literature and numbers of protein domains for all 650 ISE gene is again weakly positive (+0.7 domains per 10-fold increase in literature, r 2 = 4.2%) but is still highly significant ( p <.0001).
There was a highly significant correlation between responses to the two artemisinin derivatives ( P <0.0001).
Note the highly significant (−log10(p)≥4; p≤0.0001) differences for the left and right frontal pole, left and right insula, left and right isthmus cingulate cortex, left and right medial orbital frontal cortex, left and right rostral anterior cingulate cortex, left inferior temporal gyrus, left rostral middle frontal cortex, left temporal pole, right fusiform gyrus, right lateral orbital frontal cortex, and right parahippocampal gyrus.
The results demonstrate that essential oil type and concentration have a highly significant effect on the change in Phaeococcomyces cell count (p < 0.0001).